Episode
Genetic Pathways to Longevity: Harnessing Polygenic Risk Scores for Personalized Age-less Interventions
- Published
- Sep 6, 2025
- Duration seconds
- 1851
- Processing state
not_requested- Canonical source
- https://rss.com/podcasts/the-science-of-age-less-living/2202700
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Summary
Dive into polygenic risk scores (PRS) and discover how your genetic blueprint can inform personalized longevity strategies. Dr. Ethan Hausman-Marquis breaks down genome sequencing, five major genetic pathways to aging (DNA repair, metabolism, inflammation, mitochondria, neurodegeneration), and real-world clinical applications from The Catalyst Clinic. Learn how PRS can shift prevention from one-size-fits-all to truly individualized interventions—while understanding limits like population bias and probabilistic risk. Perfect for longevity science fans curious about precision medicine, NAD+, peptides, and building cognitive and mitochondrial resilience. If this episode helped you, please like and share with someone interested in age-less living. #PolygenicRiskScore #Longevity #PrecisionMedicine #AntiAging #Genomics OUTLINE: 00:00:00 Title and Introduction 00:02:35 Genes Aren't Destiny 00:06:19 What Is a Polygenic Risk Score? 00:10:28 Two Patients Example 00:13:17 Five Major Pathways 00:20:58 Limitations and Caveats 00:25:30 Clinical Application 00:27:56 Emotional Impact 00:29:58 Closing Reflection