Episode
Episode 188: digital therapy, DKA with SGLT2s, esketamine for resistant depression, and what is a normal TSH
- Podcast
- Primary Care Update
- Published
- Aug 29, 2025
- Duration seconds
- 1978
- Processing state
not_requested
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Summary
Join Kate, Mark, Gary and Henry as they discuss 4 great new POEMs (studies with the potential to change practice): a digital mental health intervention, the risk of DKA in patients using SGLT2 inhibitors, esketamine’s effects on suicidal ideation and unresponsive depression, and whether “one-size-fits-all” thyroid reference ranges misleading. Links: Essential Evidence Plus: www.essentialevidenceplus.com Digital mental health app for depression: https://pubmed.ncbi.nlm.nih.gov/40227715/ RIsk of DKA with SGLT2s: pubmed.ncbi.nlm.nih.gov/40070044/ Esketamine and resistant depression or suicidality: pubmed.ncbi.nlm.nih.gov/39790081/ What is a normal TSH: https://pubmed.ncbi.nlm.nih.gov/40324200/ Joseph O'Connor and the Escape Line Trilogy (2 great novels): https://www.amazon.com/The-Rome-Escape-Line-Trilogy-2-book-series/dp/B0BSNX3C89