{"podcast":{"title":"Primary Care Update","slug":"primary-care-update-1000928","podcast_index_feed_id":1000928,"rss_url":"https://anchor.fm/s/5693a5c/podcast/rss","website_url":"https://podcasters.spotify.com/pod/show/primary-care-update","image_url":"https://d3t3ozftmdmh3i.cloudfront.net/production/podcast_uploaded_nologo/807823/807823-1535146710716-0fbae5650ccb6.jpg","author":"Mark Ebell","episode_count":207,"summary":"Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/primary-care-update-1000928"},"episode":{"title":"Episode 188: digital therapy, DKA with SGLT2s, esketamine for resistant depression, and what is a normal TSH","slug":"episode-188-digital-therapy-dka-with-sglt2s-esketamine-for-resistant-depression-and-what-is-a-normal-tsh","published_at":"2025-08-29T00:52:05+00:00","page_url":"https://stenobird.com/podcast/primary-care-update-1000928/episode-188-digital-therapy-dka-with-sglt2s-esketamine-for-resistant-depression-and-what-is-a-normal-tsh","show_page_url":"https://stenobird.com/podcast/primary-care-update-1000928","url":"https://podcasters.spotify.com/pod/show/primary-care-update/episodes/Episode-188-digital-therapy--DKA-with-SGLT2s--esketamine-for-resistant-depression--and-what-is-a-normal-TSH-e37f8ib","audio_url":"https://anchor.fm/s/5693a5c/podcast/play/107503627/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2025-7-29%2Fd15f1f89-2aec-83da-5626-2ed8545ef18c.mp3","summary":"Join Kate, Mark, Gary and Henry as they discuss 4 great new POEMs (studies with the potential to change practice): a digital mental health intervention, the risk of DKA in patients using SGLT2 inhibitors, esketamine’s effects on suicidal ideation and unresponsive depression, and whether “one-size-fits-all” thyroid reference ranges misleading. Links: Essential Evidence Plus: www.essentialevidenceplus.com Digital mental health app for depression: https://pubmed.ncbi.nlm.nih.gov/40227715/ RIsk of DKA with SGLT2s: pubmed.ncbi.nlm.nih.gov/40070044/ Esketamine and resistant depression or suicidality: pubmed.ncbi.nlm.nih.gov/39790081/ What is a normal TSH: https://pubmed.ncbi.nlm.nih.gov/40324200/ Joseph O'Connor and the Escape Line Trilogy (2 great novels): https://www.amazon.com/The-Rome-Escape-Line-Trilogy-2-book-series/dp/B0BSNX3C89","meta_description":"Join Kate, Mark, Gary and Henry as they discuss 4 great new POEMs (studies with the potential to change practice): a digital mental health intervention, t…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1978,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/primary-care-update-1000928/episodes/episode-188-digital-therapy-dka-with-sglt2s-esketamine-for-resistant-depression-and-what-is-a-normal-tsh/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/primary-care-update-1000928/episode-188-digital-therapy-dka-with-sglt2s-esketamine-for-resistant-depression-and-what-is-a-normal-tsh.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}