Episode
Can We Measure Aging? The Truth About Biological Aging Clocks
- Podcast
- The ReProgram
- Published
- Feb 23, 2026
- Duration seconds
- 1685
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Summary
ReProgram Episode 9 In this episode of the Reprogram podcast, Dr. George Murphy interviews Dr. Nicholas Skivir, an expert in biological aging clocks. They discuss the differences between biological and chronological age, the complexities of measuring aging, and the construction and application of biological aging clocks. The conversation delves into factors influencing biological age, the role of disease in aging, and the potential future applications of biological aging clocks in clinical practice. The episode emphasizes the importance of understanding biological age as a metric for health and longevity. Keywords biological aging, chronological age, aging clocks, epigenetic clocks, healthspan, longevity, regenerative medicine, aging research, biological metrics, disease modeling Takeaways Biological age is a more physiological measure than chronological age. Aging clocks can predict health outcomes and morbidity. The construction of biological aging clocks involves various omics data. Epigenetic clocks are preferred due to their stability and reproducibility. Biological age can be influenced by lifestyle factors like diet and exercise. Disease can act as a driver of biological age in models. Future clinical practice may incorporate biological aging metrics. Understanding biological age can inform personalized medicine. The field of aging research is rapidly evolving with new models. Interpretability of biological aging clocks remains a challenge. Office Artifact On the desk: Bow and Quiver with Arrows; The sap of the Antiaris toxicaria tree is used to make arrow poison, historically used for hunting and warfare, Indonesia 2017 Chapters 00:00 Introduction to Biological Aging Clocks 03:21 Understanding Biological vs. Chronological Age 05:33 The Complexity of Measuring A…