Episode

#46 - Jake Orthwein | Unraveling the Dream: Psychedelics, Meditation, and the Brain

Podcast
The Metagame
Published
Apr 7, 2026
Duration seconds
4899
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not_requested
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https://themetagame.substack.com/p/46-jake-orthwein-unraveling-the-dream
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https://api.substack.com/feed/podcast/191912233/5a153b35ffac73abdc2e74d713c22716.mp3
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/v1/public/podcasts/the-metagame-5326696/episodes/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain
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/podcast/the-metagame-5326696/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain.md

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Summary

Jake Orthwein is the creator of Frame Problems , a video essay channel on science, art, philosophy, politics, and culture. In this episode, Jake talks about his upcoming film for Sam Harris ‘s mindfulness app Waking Up. We explore the latest neuroscience on consciousness and how it might explain the psychedelic experience, religious phenomenology, meditation and what it all means for a good life. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit themetagame.substack.com