# #46 - Jake Orthwein | Unraveling the Dream: Psychedelics, Meditation, and the Brain

Page: https://stenobird.com/podcast/the-metagame-5326696/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain
Text version: https://stenobird.com/podcast/the-metagame-5326696/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain.md
Podcast: [The Metagame](https://stenobird.com/podcast/the-metagame-5326696)
Published: 2026-04-07T16:28:14+00:00
Episode link: https://themetagame.substack.com/p/46-jake-orthwein-unraveling-the-dream
Audio file: https://api.substack.com/feed/podcast/191912233/5a153b35ffac73abdc2e74d713c22716.mp3
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/the-metagame-5326696/episodes/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain
Duration seconds: 4899

## Resource

Jake Orthwein is the creator of Frame Problems , a video essay channel on science, art, philosophy, politics, and culture. In this episode, Jake talks about his upcoming film for Sam Harris ‘s mindfulness app Waking Up. We explore the latest neuroscience on consciousness and how it might explain the psychedelic experience, religious phenomenology, meditation and what it all means for a good life. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit themetagame.substack.com

## Actions

- request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-metagame-5326696/episodes/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain/transcription-requests` — Idempotently request low-priority transcript generation for this episode.
- read_markdown: `GET https://stenobird.com/podcast/the-metagame-5326696/46-jake-orthwein-unraveling-the-dream-psychedelics-meditation-and-the-brain.md` — Read the agent-friendly Markdown representation of this episode resource.

A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed.

## Transcript

Full transcripts are not published on public pages unless there is a clear rights basis.