Episode
GLP-1 Side Effects Aren't Inevitable: How to Avoid Them (with Dr. Matthea Rentea)
- Published
- Dec 30, 2025
- Duration seconds
- 3427
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Summary
What if I told you that the side effects of nausea, constipation, muscle loss AND burnout on GLP-1s are not inevitable? That in many cases, they're simply a sign the medication is being used the wrong way? In this week's episode of The Holistic GLP-1 Podcast, I sit down with Dr. Matthea Rentea—a double board-certified obesity medicine physician who is quietly revolutionizing how GLP-1s are used in clinical practice. This is one of the most nuanced, compassionate and empowering conversations we've had about how using GLP-1 medications can be part of a true healing journey—not a crash-and-burn weight loss strategy. *** SHOW NOTES [ 00:00 ] Introduction [ 01:20 ] How GLP-1s Changed Obesity Medicine [ 05:05 ] Why Dr. Rentea Practices Holistic Medicine [ 06:45 ] Dosing Strategy: Why The "Lowest Effective Dose" Works Best [ 10:00 ] Carbohydrates, Insulin Resistance & Food Ordering [ 13:40 ] How to Identify Insulin Resistance Early [ 16:50 ] Why Side Effects Are Often Preventable [ 18:40 ] Protein, Fiber & Protecting Muscle and Longevity [ 22:20 ] Lean Mass vs. Skeletal Muscle Mass [ 25:20 ] Bone Health, Strength Training & Aging [ 28:30 ] Mindset, Identity & Behavior Change [ 33:10 ] Dr. Rentea's Personal Weight Journey [ 36:20 ] Are GLP-1s Lifelong? [ 41:00 ] Can You "Re-sensitize" to GLP-1s? [ 45:10 ] Genetics, Satiety Signaling & Healing Shame [ 50:30 ] Supplements on a GLP-1 Journey [ 54:50 ] What Real Success Looks Like on GLP-1s *** 🔗 Mentioned in This Episode: CLICK HERE TO GET ⇒ Free Masterclass: Freedom From Food Noise: https://go.elizabethmcgann.com/start *** Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: ht…