Episode
Louisa Nicola: Why Women Are at 6X the Alzheimer's Risk (And the Exercise Protocol That Fixes It) | #153
- Podcast
- The Dr Vonda Show
- Published
- Mar 24, 2026
- Duration seconds
- 2947
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Summary
Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity Your brain is not losing its mind by accident. It has been compounding every decision you've made for the last thirty years. Louisa Nicola is one of my closest friends, and one of the most brilliant neurophysiologists working today, an elite triathlete and PhD researcher who has dedicated her life to understanding how the brain ages and, more importantly, how to stop it from declining. In this episode, Louisa and I pull back the curtain on everything you thought you knew about Alzheimer's disease, starting with the truth about amyloid, the protein we've been blaming for decades that is actually your brain's own defense system, and we build you a real, science-backed brain insurance policy: the specific exercise protocols, sleep requirements, hormonal factors, and daily habits that determine whether your mind stays sharp and fully yours well into your eighties and beyond. What we cover: - How amyloid, long blamed as the villain of Alzheimer's disease, is actually your brain's own antimicrobial defense system. - Why Alzheimer's begins silently in your thirties and forties, not your eighties, compounding over decades. - What cognitive reserve means at the cellular level and how to build more of it starting now. - The specific exercise protocols, including resistance training and zone five, that protect your brain most. - How deep sleep triggers your brain's nightly cleaning system and why skipping it accelerates decline. - Why doing hard things, and learning new skills across your lifespan, physically grows your brain. About Louisa Nicola: Louisa…