Episode
#41 Cracking the genetic code of complex chronic illness with Steve Gardiner, PrecisionLife
- Published
- Sep 7, 2026
- Duration seconds
- 3165
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Summary
PrecisionLife are cracking the genetic code on ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) and Long COVID. Through large-scale studies with DecodeME, the LOCOME Project, Sano Genetics’ Gold dataset, and the All of Us research programme, PrecisionLife have identified hundreds of genes associated with Long COVID and ME/CFS, revealing distinct patient phenotypes and pointing to how each might be treated. This week, PrecisionLife CEO Steve Gardner explains why these findings mark a transformational point for ME/CFS and Long COVID. He covers what the genetics reveal, why stratification is essential in clinical trials, and the 42 repurposed drug candidates identified so far. Steve believes this represents a profound shift in how we understand, diagnose and treat ME/CFS and Long COVID, made possible through collaboration with the Complex Disorders Alliance, Action for ME, Innovate UK and the Metrodora Institute.