# #41 Cracking the genetic code of complex chronic illness with Steve Gardiner, PrecisionLife

Page: https://stenobird.com/podcast/make-visible-chronic-illness-explored-7015207/41-cracking-the-genetic-code-of-complex-chronic-illness-with-steve-gardiner-precisionlife
Text version: https://stenobird.com/podcast/make-visible-chronic-illness-explored-7015207/41-cracking-the-genetic-code-of-complex-chronic-illness-with-steve-gardiner-precisionlife.md
Podcast: [Make Visible: ME/CFS, Long Covid, POTS, EDS, Fibro & MCAS Explored](https://stenobird.com/podcast/make-visible-chronic-illness-explored-7015207)
Published: 2026-09-07T09:20:14+00:00
Episode link: https://madevisible.podbean.com/e/41-cracking-the-genetic-code-in-mecfs-long-covid-with-steve-gardiner-precisionlife/
Audio file: https://mcdn.podbean.com/mf/web/kqbctuijwt6ajn7i/Visible_S1_Ep41_Steve_Gardner.mp3
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Duration seconds: 3165

## Resource

PrecisionLife are cracking the genetic code on ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) and Long COVID. Through large-scale studies with DecodeME, the LOCOME Project, Sano Genetics’ Gold dataset, and the All of Us research programme, PrecisionLife have identified hundreds of genes associated with Long COVID and ME/CFS, revealing distinct patient phenotypes and pointing to how each might be treated. This week, PrecisionLife CEO Steve Gardner explains why these findings mark a transformational point for ME/CFS and Long COVID. He covers what the genetics reveal, why stratification is essential in clinical trials, and the 42 repurposed drug candidates identified so far. Steve believes this represents a profound shift in how we understand, diagnose and treat ME/CFS and Long COVID, made possible through collaboration with the Complex Disorders Alliance, Action for ME, Innovate UK and the Metrodora Institute.

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