Episode
Ep339: What’s Really Driving Your Weight Loss Resistance After 40? with Curtis Gillespie Sayers
- Podcast
- Fit + Fueled Life Podcast
- Published
- May 26, 2026
- Duration seconds
- 3830
- Processing state
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- http://cast.rocks/hosting/28841/Ep339-What-s-Really-Driving-Your-Weight-Loss-Resistance-After-40.mp3
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Summary
In this episode, Tina sits down with Curtis to dig into what’s really behind weight loss resistance after 40. Because for a lot of women, it’s not just about calories, macros, or workouts. It’s everything happening underneath: chronic stress, inflammation, under-eating, nervous system overload, and a body that’s quietly shifting into protection mode in midlife. They also talk about why fat loss can suddenly stall, what most people miss when they try to “push harder,” and how things like detox pathways, recovery, and unresolved stress load all show up in body composition. If you’ve been doing more and getting less back, this conversation helps connect a lot of those dots. Here’s what you’ll learn: - The real reason you can't lose weight has nothing to do with your macros or your workouts - Why your body is literally designed to hold onto fat and what has to happen before it will let go - The connection between unresolved trauma and weight loss resistance that Curtis sees in almost every woman who has tried everything - Detox is fat loss: what this actually means and why your ability to detoxify determines whether your body will release fat - Why under-eating is making fat loss harder and the slow strategic way to fix it - What food noise is actually telling you and why a GLP-1 not quieting it down is a very specific clue - The training style most women swear by that Curtis says is creating more inflammation than results - Why your body will never prioritize building muscle when you are under-eating and inflamed - The mitochondrial peptides everyone is using for fat loss that Curtis thinks are being used completely backwards - Why MOTS-c works great for some women and causes serious reactions in others - Two books that have changed more of his clients' biology than any p…