Episode

New Approaches: Marstacimab Therapy and HLH Biomarkers

Podcast
Blood Podcast
Published
May 28, 2026
Duration seconds
1070
Processing state
not_requested
Canonical source
https://share.transistor.fm/s/18f11dc5
Audio
https://prfx.byspotify.com/e/media.transistor.fm/18f11dc5/085b0d58.mp3
JSON
/v1/public/podcasts/blood-podcast-664776/episodes/new-approaches-marstacimab-therapy-and-hlh-biomarkers
Markdown
/podcast/blood-podcast-664776/new-approaches-marstacimab-therapy-and-hlh-biomarkers.md

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Summary

In this week's episode, Blood editor Dr. James Griffin interviews Drs. Johnny Mahlangu and Joseph Rocco on their articles published in volume 147 issue 9 of Blood . Dr. Mahlangu discusses study details and next steps from " Efficacy and safety of marstacimab prophylaxis in hemophilia A/B with inhibitors: results from the phase 3 BASIS trial " which shows that bleeding was reduced by 93% with subcutaneous marstacimab. Dr. Rocco shares the development behind " CXCL9 as a novel prognostic marker to identify high-risk adults with hemophagocytic lymphohistiocytosis ", and the insights gained from measuring a new surrogate marker of IFN-γ activity predicting severity and mortality.