Episode

The Skincarma Pod | Ep. 73: NAD⁺ — The Molecule Everyone Wants to Boost, But No One Can Measure with Jari Närhi, NADMED CEO

Podcast
The Skincarma® Pod
Published
Apr 19, 2026
Duration seconds
1801
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https://skincarma.substack.com/p/the-skincarma-pod-ep-73-nad-the-molecule
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Summary

Everyone is talking about boosting NAD⁺. Almost no one is measuring it. In the world of longevity, NAD⁺ has become one of the most talked-about — and most aggressively marketed — molecules. From supplements to IV drips, the focus is on increasing NAD levels in the body. But there’s a fundamental question that rarely gets asked: How do you know if your NAD actually needs to be boosted in the first place? In this episode, Carmine sits down with Jari Närhi, CEO of NADMED , a Finnish health technology company developing one of the first clinical blood tests designed to measure NAD levels accurately and at scale. Together, they explore the science behind NAD — what it is, what it does in the body, and why it has become central to the longevity conversation. But more importantly, they unpack the measurement gap that has shaped the entire category. For decades, NAD has been notoriously difficult to measure due to its instability outside of cells — meaning much of the conversation around boosting NAD has been built on assumptions, not data. That’s where NADMED comes in. By developing a laboratory assay capable of measuring multiple forms of NAD in whole blood, they’re opening the door to something that has long been missing in the space: objective insight. This episode reframes the NAD conversation — not as something to blindly optimize, but as something to first understand. You’ll learn: • What NAD⁺ is and why it’s essential for cellular energy and metabolic function;• Why NAD exists in multiple forms — and why that matters for measurement;• The role NAD plays in processes like DNA repair, cell signaling, and aging;• Why NAD has been historically difficult to measure in blood;• How instability and degradation have limited real-world testing;• What NADMED’s breakthrough assay…