Episode
Gene Therapy for Parkinson's: Myths vs. Facts
- Podcast
- The Parkinson's Podcast
- Published
- Nov 17, 2025
- Duration seconds
- 1893
- Processing state
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Summary
In this episode of the Parkinson's Podcast, l earn about gene therapy for Parkinson's , including common misunderstandings and ongoing research about it. This episode contains some technical terms and abbreviations. For your convenience , here is a short list o f definitions that might be helpful. AADC – Aromatic L-Amino Acid Decarboxylase: An enzyme that helps make dopamine (not a rock and roll band) AAV – Adeno-Associated Virus: A harmless virus used to deliver gene therapy CDNF – Cerebral Dopamine Neurotrophic Factor: A protein that helps keep dopamine-producing cells healthy DBS – Deep Brain Stimulation: A surgical treatment that uses electrical signals to help control symptoms GAD – Glutamic Acid Decarboxylase: An enzyme that helps rebalance brain circuits. GBA – A gene linked to Parkinson's risk GCH1 – GTP Cyclohydrolase 1: An enzyme that supports dopamine production. GDNF – Glial Cell Line-Derived Neurotrophic Factor: A protein that helps protect brain cells LRRK2 – A gene linked to Parkinson's risk PARK2 – A gene linked to Parkinson's risk PET – Positron Emission Tomography: A brain scan that shows chemical activity PINK1 – A gene linked to Parkinson's risk SNCA – A gene linked to Parkinson's risk More information about Gene Therapy for Parkinson's is available here: https://davisphinneyfoundation.org/blog/gene-therapy-parkinsons/ https://youtu.be/n2KNtRK3SIk https://youtu.be/v9mJiO4EEag Sign up for updates on webinars, events, and resources for the Parkinson's community: https://dpf.org/newsletter-signup