Episode
Quick Hits: The Women's Hormone Masterclass: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain with Dr. Kyle Gillett
- Published
- Mar 10, 2026
- Duration seconds
- 1063
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Summary
Listen to the full episode Download the full episode on Apple or on your favorite podcast platforms. In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass. In this episode we discuss: How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being. Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability. Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance. How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens. Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes. The role of DHT blockers in managing androgen-related conditions. How SHBG can be harnessed for overall hormone stability and health benefits. Challenges of menopausal weight gain and how hormonal changes affect body composition. Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss. How to maintain lean body mass through hormone therapy and lifestyle changes. How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance. The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives. Exploring differ…