Episode
How to Stop GLP-1's Without Gaining the Weight Back (with Dr. Holly Wyatt)
- Published
- Feb 24, 2026
- Duration seconds
- 3173
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Summary
One of the biggest fears women have when starting GLP-1 medications isn't losing the weight —it's what happens after. Do I have to stay on this forever? Will I regain the weight if I stop? Is there a right way to transition into maintenance? In this powerful, science-grounded episode, Elizabeth sits down with Dr. Holly Wyatt—endocrinologist, obesity medicine physician, and author of Losing the Weight Loss Meds—to explore what actually helps people keep weight off long-term, with or without medication. This conversation bridges medical science with real-world behavior change, mindset, identity, and lifestyle—and fits seamlessly into the Holistic GLP-1 Method. If you're thinking about maintenance, transition, or long-term freedom from food struggle, this episode is essential listening. *** SHOW NOTES [ 00:00 ] Introduction [ 02:30 ] Why Dr. Wyatt wrote a book about getting OFF GLP-1s [ 03:55 ] Do you really have to stay on GLP-1s for life? [ 04:25 ] Why weight regain happens [ 05:20 ] What the data tells us (and what we're still learning) [ 07:45 ] GLP-1s as "training wheels" [ 08:30 ] Begin with the end in mind [ 09:05 ] The three pillars of successful maintenance [ 10:00 ] Why environment can make or break maintenance [ 11:20 ] Blood sugar, appetite & GLP-1 physiology (made simple) [ 13:25 ] Can lifestyle replace medication effects? [ 14:40 ] Quality vs. quantity of weight loss [ 15:20 ] The Appetite Reset Meal [ 17:40 ] Why breakfast matters more than you think [ 19:30 ] No dogma: one size never fits all [ 20:05 ] The Satiety Snack strategy [ 22:30 ] Physical activity is for maintenance, not weight loss [ 23:05 ] Metabolic flexibility explained [ 24:30 ] Why some people's weight never changes [ 26:10 ] The Supper Club strategy [ 27:55 ] The #1 mistake when stopping GL…