Episode
#113 - Meet The Neuroscientist Decoding Your Bodies Cannabis System
- Podcast
- Giants Shoulder
- Published
- Apr 22, 2026
- Duration seconds
- 3866
- Processing state
not_requested
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Summary
Dr. Matt Hill is one of the world’s leading cannabis neuroscientists, former president of the International Cannabinoid Research Society, and a researcher with over 21,000 citations studying how the endocannabinoid system regulates the brain and body.Cannabis affects different people in completely opposite ways — calming one person while causing crippling anxiety in another — and Hill explains why the biology makes this inevitable, why both sides of the cannabis debate are getting it wrong, and why legalisation in Canada accidentally destroyed the very research that could have answered our biggest questions.Expect to learn why CB1 is the most widely distributed receptor in the brain yet almost nobody has heard of it, how endocannabinoids work backwards across the synapse unlike any other signalling system, why low-dose THC calms the amygdala but high-dose THC causes paranoia and anxiety, why women get higher than men on the same dose of cannabis due to a liver enzyme difference, why only a third of people genuinely benefit from medical cannabis while a third get nothing, how cannabis triggers schizophrenia in genetically vulnerable people without actually causing the disease, why Canadian legalisation killed cannabis clinical trials through a bureaucratic GMP-versus-GPP standoff, what the real cardiovascular risks of chronic cannabis use are, why cannabis users paradoxically have lower obesity rates, and much more…Timestamps: 00:00 Trailer02:00 Dr. Matt Hill — Cannabis Neuroscientist02:25 The Endocannabinoid System: Your Body’s Own Cannabis04:23 Every Biological Function It Controls06:30 The Most Distributed Receptor Nobody’s Heard Of07:20 Why Cannabis Science Is So Politically Toxic09:35 Both Sides Are Wrong: The Three Blind Men Problem10:23 The Frustrating Polarity o…