Episode
The Gary Null Show - 7-24-26
- Podcast
- The Gary Null Show
- Published
- Jul 24, 2026
- Duration seconds
- 3352
- Processing state
not_requested
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Summary
HEALTH NEWS Curcumin shows the best balance against cancer, study shows First trial confirms swimming reduces disability from chronic back pain Nanoplastics in Drinking Water May Be Making Dangerous Bacteria Stronger, New Study Warns Kids remember veggie scents from womb, study finds Watermelon Contains Compounds Linked to Cardiovascular and Metabolic Health, Studies Show Curcumin shows the best balance against cancer, study shows Wroclaw Medical University (Poland), July 22 2026 (News-Medical) Curcumin, berberine, and other plant-derived compounds have long attracted scientific interest because of their anti-inflammatory and anticancer properties. A new study by researchers from Wroclaw Medical University, however, shows that not all natural compounds act in the same way, and strong anticancer activity does not always go hand in hand with a good safety profile. The researchers compared five compounds: curcumin, berberine, biochanin A, cucurbitacin E, and CAPE (caffeic acid phenethyl ester), a component of propolis. They investigated how these substances affected fibrosarcoma cells and healthy muscle cells. The study focused on the NF-κB signaling pathway, which regulates inflammation, metabolism, cell survival, and cellular aging. The tested compounds disrupted mitochondrial function, reducing the cancer cells’ ability to produce energy. In fibrosarcoma cells, ATP levels decreased by approximately 83–92%, compared with reductions of around 23–73% in healthy muscle cells. This suggests that cancer cells are more vulnerable to disturbances in energy metabolism. The compounds also affected mitophagy, the process responsible for removing damaged mitochondria. All five compounds induced features of cellular senescence in fibrosarcoma cells. In this state, cells remain aliv…