Episode

The Laughing Sickness: Medicine’s Strangest Cold Case

Podcast
Mysteries and Histories
Published
Aug 3, 2026
Duration seconds
1387
Processing state
not_requested
Canonical source
https://podcasters.spotify.com/pod/show/georgiamariexo/episodes/The-Laughing-Sickness-Medicines-Strangest-Cold-Case-e3mt9nu
Audio
https://traffic.megaphone.fm/APO1126678033.mp3
JSON
/v1/public/podcasts/mysteries-and-histories-1576928/episodes/the-laughing-sickness-medicine-s-strangest-cold-case
Markdown
/podcast/mysteries-and-histories-1576928/the-laughing-sickness-medicine-s-strangest-cold-case.md

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Summary

In the isolated highlands of Papua New Guinea, a strange and horrifying disease spread through entire villages, leaving women and children trembling, stumbling, and erupting into sudden fits of laughter before wasting away to death. For years, no one knew what was killing them, and the answer turned out to be far more disturbing than anyone expected: a fatal prion disease tied to one of the greatest human taboos.