Episode
BITESIZE: Results from first RCT of Keto for Schizophrenia + Bipolar: Metabolic Wins & Mental Health Signals
- Podcast
- Metabolic Mind
- Published
- Jul 8, 2026
- Duration seconds
- 253
- Processing state
not_requested- Canonical source
- https://metabolicmind.org/
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Summary
New evidence from the first-ever RCT shows ketogenic therapy can rapidly improve metabolic health in schizophrenia-spectrum and bipolar I disorders, and shows early signals of psychiatric improvement. In this video, Dr. Bret Scher breaks down this newly published study led by Dr. Judith Ford at UCSF: the first randomized controlled trial with peer-reviewed results investigating ketogenic therapy in people with schizophrenia-spectrum disorders and bipolar-1 disorder with psychotic features. You’ll learn: How the study was designed (a 1-month randomized phase plus an optional 3-4 month single-arm extension) What happened in the first 30 days (clear improvements in metabolic markers; psychiatric outcomes showed trends that did not reach statistical significance in the randomized portion) What improved over longer follow-up in the extension phase (encouraging changes in metabolic health, cognition, and psychiatric measures) Why this matters for patients and families today, and what future, longer controlled trials need to confirm Published in Schizophrenia Bulletin and funded by the NIMH and Baszucki Group, this study adds to the growing literature on the potential benefit of ketogenic therapy for psychiatric disorders. These results indicate the need for larger, extended randomized controlled trials to test the safety and efficacy of ketogenic therapy in patients living with serious mental illness. 👉 Learn more about the study by visiting our website: https://www.metabolicmind.org/trials/featured-post/peer-reviewed-results-of-first-ever-randomized-controlled-trial-of-ketogenic-diet-in-schizophrenia-spectrum-and-bipolar-i-disorder/ 🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Meta…