Episode

From the archive: Philosophers on psychedelics

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Many Minds
Published
Jul 17, 2026
Duration seconds
6049
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Summary

Hi friends! We're taking a bit of a summer pause. We will be back soon—in the meanwhile, enjoy this listener favorite from our archives! ----- [originally aired May 14, 2025] Some call it the "psychedelic renaissance." In the last decade or so, interest in psychedelic drugs has surged—and not just among Silicon Valley types and psychiatrists and neuroscientists. It's also surged among a stereotypically soberer crowd: academic philosophers. The reasons are clear. With their varied and sometimes transformative effects, psychedelics raise ethical questions, epistemological questions, metaphysical questions, questions about the nature of experience and the nature of the mind. My guest today is Dr. Chris Letheby . Chris is a philosopher of cognitive science at the University of Western Australia and the author of the 2021 book, Philosophy of Psychedelics . Here, Chris and I talk about the so-called classic psychedelics—LSD, psilocybin, ayahuasca, and others—and how interest in them has gone through three distinct waves. We discuss the effects that these substances seem to have, in particular their capacity to treat certain psychiatric conditions and their tendency to induce "mystical-like" experiences. We consider the idea that psychedelics might serve as agents of moral enhancement. And we dig into the psychological and neural mechanisms by which psychedelics seem to have their diverse—and often salutary—effects. Along the way, we talk about ontological shock, comforting delusions, brain plasticity, unselfing, microdosing, placebo effects and adverse effects, physicalism and idealism, the REBUS model, environmental virtues, plant consciousness, meditation, and much more. Maybe this is obvious but this episode is not just for the seasoned psychonauts out there. Whatever you…