Episode
From Experience to Evidence: How Data-Driven Ketamine Treatment Is Combatting Depression
- Podcast
- Living Medicine
- Published
- Jan 15, 2026
- Duration seconds
- 3059
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Summary
Nicolas Grundmann is the Co-founder and CEO of Ember Health, which provides IV ketamine treatments for depression. As a board-certified emergency medicine physician, he launched Ember Health to create more effective, patient-centered treatment options. Nicolas is also a faculty member at the American Society of Ketamine Physicians, Psychotherapists and Practitioners, and is the Co-founder of Chenla Children's Healthcare, which improves pediatric care in Cambodia. In this episode… Mental health treatment is evolving as clinicians search for options that outperform traditional approaches. From data-driven care to treating trauma, anxiety, and depression together, how can clinicians create evidence-based ketamine treatments? According to emergency medicine physician Nicolas Grundmann, effective ketamine treatment starts with rigorous evidence, longitudinal data, and close care coordination. He emphasizes symptom-driven dosing, regular measurement using validated tools, and proactive follow-up to catch relapses early. Clinicians should also integrate outside therapists, help patients relearn emotional regulation after depression lifts, and avoid one-size-fits-all models. In this episode of Living Medicine , Dr. Sandy Newes talks with Nicolas Grundmann, Co-founder and CEO of Ember Health, about evidence-based ketamine treatment for depression. Nicolas talks about using real-world data to guide care, treating depression with comorbid PTSD and anxiety, and whether to include therapy during ketamine sessions.