Episode
Ep. 614 "The Progesterone Conversation We've Been Missing" | Menopause, Perimenopause, Progesterone
- Published
- Jul 2, 2026
- Duration seconds
- 1948
- Processing state
not_requested- Canonical source
- https://traffic.megaphone.fm/CTH7897644936.mp3
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Summary
Welcome to this week’s Midlife Minute. In this episode, we’re focusing on progesterone, exploring the differences between progesterone and progestins, how progesterone is used in clinical practice, and how individual responses can vary significantly. IN THIS EPISODE, YOU WILL LEARN: Why bioidentical progesterone and synthetic progestins are not interchangeable How early synthetic progestin studies continue to shape how progesterone is viewed How different routes of progesterone administration produce different effects Why do some women experience stronger neurological or physical effects than others on the same progesterone dose How cyclical versus continuous use can affect how progesterone is used in the body Why some women experience sleep or mood changes on oral progesterone The importance of personalized decision-making Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Resources: The pharmacodynamics and safety of progesterone doi:10.1016/j.bpobgyn.2020.06.002 Profiles of plasma estrogens, progesterone and their metabolites after oral or vaginal administration of estradiol or progesterone doi:10.1016/0378-5122(93)90064-O Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone doi:10.1016/j.maturitas.2005.11.005 Allopregnanolone and mood in the peripartum: a longitudinal assessment in healthy women doi:10.1016/j.psyneuen.2019.104465 Behavior of Male Gamete Fusogen GC…