{"podcast":{"title":"Weight Loss And ...","slug":"weight-loss-and-6741102","podcast_index_feed_id":6741102,"rss_url":"https://feeds.transistor.fm/weight-loss-and","website_url":"https://www.weightlossand.com","image_url":"https://img.transistorcdn.com/nU4J861NxgZgwWoAyLH39jUsjeqMrjyOtBeq7lRHQUg/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8yOWI3/NGNmNTdhY2VjYTZi/OTYxZGQ4NTZlZjk1/NmI5Yy5qcGc.jpg","author":"Holly Wyatt & James Hill","episode_count":137,"summary":"Your go-to hangout for everything weight loss… and beyond! “Weight Loss and…” is brought to you by the University of Alabama at Birmingham (UAB) and hosted by seasoned experts in weight management, Dr. James Hill and Dr. Holly Wyatt. We’re your friendly guides through the maze of weight loss, but with a fun twist. We’re not here to preach the latest fad diet or promise a miracle workout. Instead, we’re all about embracing the journey, acknowledging there’s more than one way to hit your health goals, and having a good laugh while we’re at it. We get it: weight loss can be tough, and sometimes pretty serious business. But why can’t it also be enjoyable? With a side of humor, we’ll bring you science-backed insights, real-life stories, and some hard truths. (Spoiler alert: there’s no magic answer - but that doesn’t mean we can’t find what works best for you.) “Weight Loss and…” is your inclusive space to explore, question, and learn — and to feel part of a community along the way. This isn’t just about shedding pounds. It’s about gaining perspective, building better habits, and enjoying the ride. So if you’re up for honest conversations about weight loss - spiced with a little science…","last_synced_at":"2026-07-22T22:18:08.586989+00:00","page_url":"https://stenobird.com/podcast/weight-loss-and-6741102"},"episode":{"title":"How GLP-1 Medications Changed the Science and Art of Sustainable Weight Loss with Arne Astrup","slug":"how-glp-1-medications-changed-the-science-and-art-of-sustainable-weight-loss-with-arne-astrup","published_at":"2026-01-21T12:00:00+00:00","page_url":"https://stenobird.com/podcast/weight-loss-and-6741102/how-glp-1-medications-changed-the-science-and-art-of-sustainable-weight-loss-with-arne-astrup","show_page_url":"https://stenobird.com/podcast/weight-loss-and-6741102","url":"https://weightlossand.com/how-glp-1-medications-changed-the-science-and-art-of-sustainable-weight-loss-with-arne-astrup","audio_url":"https://media.transistor.fm/79ca5c26/85006dfe.mp3","summary":"The GLP-1 medications transforming weight loss didn’t appear overnight. They’re the result of decades of groundbreaking research that fundamentally changed how we understand appetite and obesity. But how did scientists first discover that this hormone could help people lose weight? And what does this history mean for anyone using these medications today? Join Holly and Jim as they sit down with Dr. Arne Astrup, one of the pioneering researchers who helped uncover GLP-1’s role in appetite regulation back in the 1990s. Dr. Astrup has spent over three decades at the forefront of obesity research at the University of Copenhagen and the Novo Nordisk Foundation. In this fascinating conversation, he takes us back to when obesity was still seen as a willpower problem, reveals the serendipitous collaboration that led to discovering GLP-1’s satiety effects, and shares critical insights about using these medications safely and effectively. Whether you’re currently using GLP-1 medications, considering them, or simply curious about the science, this episode offers essential perspective from someone who’s witnessed the entire journey from early physiology experiments to today’s real-world treatments. You’ll discover why lifestyle still matters in the era of highly effective medications, and walk away with a deeper understanding of both the promise and the limitations of these groundbreaking drugs. Discussed on the episode: The surprising mindset shift in the 1990s that changed how medicine views obesity Why a diabetes researcher and an appetite scientist became unlikely collaborators The first human experiment that proved GLP-1 reduces hunger (and the lunch buffet that made it possible) Why GLP-1 medications are so much “cleaner” than previous weight loss drugs The protein malnutrit…","meta_description":"The GLP-1 medications transforming weight loss didn’t appear overnight. They’re the result of decades of groundbreaking research that fundamentally change…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2679,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/weight-loss-and-6741102/episodes/how-glp-1-medications-changed-the-science-and-art-of-sustainable-weight-loss-with-arne-astrup/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/weight-loss-and-6741102/how-glp-1-medications-changed-the-science-and-art-of-sustainable-weight-loss-with-arne-astrup.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}