{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Parkinson’s in the Clinic, Insilico enters Phase III, Vertex Acquires Crinetics","slug":"parkinson-s-in-the-clinic-insilico-enters-phase-iii-vertex-acquires-crinetics","published_at":"2026-07-17T01:51:51+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/parkinson-s-in-the-clinic-insilico-enters-phase-iii-vertex-acquires-crinetics","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/parkinsons-in-the-clinic-insilico-enters-phase-iii-vertex-ac","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/6a598ab67a878a3380370304/media.mp3","summary":"Promise hits Parkinson’s disease therapy, as a Phase I/II clinical study has demonstrated the feasibility of transplanting stem-cell-derived dopamine progenitor cells into the brain. In preclinical research, a new platform uses the brain’s fluid transport pathways to effectively deliver AAVs to therapeutic targets in mice. We’ll also cover the accelerating infrastructure moment for AI-driven drug discovery, with billion-dollar investments flowing into end-to-end platforms driven by models and compute, rather than single drug assets. In business, Insilico’s revenue leaps as the company’s AI-developed lead candidate moves to Phase III, while Vertex acquires Crinetics for $10 billion.     Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news.       Listed below are links to the GEN stories referenced in this episode of Touching Base :     Engineered AAVs Harness Glymphatic System to Reach Brain Targets in Mice   GEN , July 9, 2026    Stem Cell Therapy Shows Promise in First Human Parkinson’s Disease Trial   GEN , July 9, 2026    Pharma Races to Scale AI as Billions Flow into Drug Discovery   By Fay Lin, PhD, GEN Edge , July 6, 2026    StockWatch: Insilico Projects Profit, Revenue Leaps as AI-Developed Lead Candidate Moves to Phase III   By Alex Philippidis, GEN Edge , July 12, 2026    Vertex Eyes Expansion Beyond Cystic Fibrosis with Planned $10B Crinetics Buyout   By Alex Philippidis, GEN Edge , July 7, 2026    Top 20 Drugs Heading for the Patent Cliff, 2026-2029   By Alex Philippidis, GEN Magazine , Nov 1, 2025    Touching Base Podcast   Hosted…","meta_description":"Promise hits Parkinson’s disease therapy, as a Phase I/II clinical study has demonstrated the feasibility of transplanting stem-cell-derived dopamine prog…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1942,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/parkinson-s-in-the-clinic-insilico-enters-phase-iii-vertex-acquires-crinetics/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/parkinson-s-in-the-clinic-insilico-enters-phase-iii-vertex-acquires-crinetics.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}