{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Nobel Prizes Announced and Breakthroughs for Huntington’s and Rare Diseases","slug":"nobel-prizes-announced-and-breakthroughs-for-huntington-s-and-rare-diseases","published_at":"2025-10-10T13:16:41+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/nobel-prizes-announced-and-breakthroughs-for-huntington-s-and-rare-diseases","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/nobel-prizes-announced-and-breakthroughs-for-huntingtons-and","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/68e90723f513ad2b8114eb3d/media.mp3","summary":"Metal-organic frameworks and peripheral immune tolerance were the big winners of the Nobel prizes in chemistry, and in physiology or medicine, respectively. In this episode of the podcast, we discuss the winners and the impacts of their discoveries. Then we move over to some business news where we discuss a novel gene therapy for Huntington’s disease from uniQure that made waves recently. Early clinical trial data for AMT-130 showed that it could meaningfully slow the progression of the disease by as much as 75%. Also in business news, a new partnership involving Arbor Biotechnologies and Chiesi Group aims to develop gene editing therapies to target rare liver diseases. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news.  Listed below are links to the GEN stories referenced in this episode of Touching Base : Brunkow, Ramsdell, Sakaguchi Win Nobel Prize in Physiology or Medicine for Peripheral Immune Tolerance Uduak Thomas, GEN , October 6, 2025 Metal-Organic Frameworks Win the 2025 Nobel Prize in Chemistry Julianna LeMieux, PhD, GEN , October 8, 2025 Gene Therapy Significantly Slows Huntington Disease Progression GEN, September 24, 2025   StockWatch: uniQure Shares Reach Five-Year High on “Game Changing” Huntington’s Data Alex Philippidis , GEN Edge, September 28, 2025   Chiesi, Arbor Target Rare Liver Diseases in Up-to-$2.1B Gene Editing Collaboration Alex Philippidis, GEN Edge, October 8, 2025 Touching Base Podcast Hosted by Corinna Singleman, PhD Hosted on Acast. See acast.com/privacy for more information.","meta_description":"Metal-organic frameworks and peripheral immune tolerance were the big winners of the Nobel prizes in chemistry, and in physiology or medicine, respectivel…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1260,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/nobel-prizes-announced-and-breakthroughs-for-huntington-s-and-rare-diseases/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/nobel-prizes-announced-and-breakthroughs-for-huntington-s-and-rare-diseases.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}