{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Lung Organoids, Autism and Sarcopenia Insights in Mice, and a Bidding War Ends","slug":"lung-organoids-autism-and-sarcopenia-insights-in-mice-and-a-bidding-war-ends","published_at":"2025-12-04T22:27:26+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/lung-organoids-autism-and-sarcopenia-insights-in-mice-and-a-bidding-war-ends","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/lung-organoids-autism-and-sarcopenia-insights-in-mice-and-a","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/69320ae6a63c6eaa591a90c9/media.mp3","summary":"Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas including an automated method for manufacturing iPSC-derived lung organoids and how a combination of supplements reduced autism-linked behaviors in mice. Still on the topic of new research, we discussed how a protein in the extracellular matrix helps muscle stem cells repair aging muscles. In business news, the bidding war between Lundbeck and Alkermes over Avadel Pharmaceuticals has ended. We talk about the possible implications of Lundbeck’s decision to back out and next steps for Alkermes. Then we dive into Protego Biopharma’s recent fundraising round, and efforts to develop small-molecule pharmacological chaperones that modulate protein stability in disease.     Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news.    Listed below are links to the GEN stories referenced in this episode of Touching Base :    Lung Organoids Generated in Bulk Using Stirred Bioreactor Technology GEN , December 1, 2025 Autism-Linked Behaviors in Mice Reduced by Nutrient Trio GEN , December 3, 2025 Muscle Stem Cells Bolstered by ECM Protein Tenascin-C GEN , December 5, 2025   Protego Closes $130M Series B to Fund Pivotal Trial of AL Amyloidosis Candidate By Alex Philippidis, GEN Edge, December 3, 2025 Lundbeck Ends Bidding War for Avadel, After Alkermes’ Up-to-$2.37B Offer By Alex Philippidis, GEN Edge, December 1, 2025 Touching Base Podcast   Hosted by Corinna Singleman, PhD    Behind the Breakthroughs   Hosted by Jonathan D. Grinstein, PhD  Hosted on Acast. See acast.com/privacy for more information.","meta_description":"Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas includi…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2156,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/lung-organoids-autism-and-sarcopenia-insights-in-mice-and-a-bidding-war-ends/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/lung-organoids-autism-and-sarcopenia-insights-in-mice-and-a-bidding-war-ends.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}