{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Developing New Therapies Through Partnership, Electricity, and Immunotherapy","slug":"developing-new-therapies-through-partnership-electricity-and-immunotherapy","published_at":"2025-09-05T13:50:09+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/developing-new-therapies-through-partnership-electricity-and-immunotherapy","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/developing-new-therapies-through-partnership-electricity-and","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/68baea94f8dc6bde3858318e/media.mp3","summary":"Novartis has agreed to license and develop Arrowhead Pharmaceuticals’ preclinical stage small interfering RNA (siRNA) therapy ARO-SNCA, a potential treatment for Parkinson’s disease and other synucleinopathies, plus additional targets. Two stories this week covered very different types of cell reprogramming techniques for therapy development. The first approach may overcome the time delays and safety risks of traditional immunotherapies, especially for patients with aggressive, late-stage disease. Meanwhile, electrical stimulation of macrophages could represent a new therapy to boost the body’s own repair processes in a range of injury and disease situations. Finally, Eli Lilly saw its shares climb 5% this past week after announcing that its history-making oral obesity candidate, orforglipron, aced the Phase III ATTAIN-2 trial. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base : The State of Biotech Summit Registration Novartis Commits Up to $2.2B toward Developing Arrowhead siRNA Therapy Alex Philippidis , GEN Edge, September 2, 2025 Off-the-Shelf Immunotherapy Demonstrates Multipronged Attack Against Cancer GEN, August 29, 2025 Human Macrophages “Reprogrammed” by Electrical Stimulation to Encourage Faster Healing GEN, September 2, 2025 StockWatch: Analysts See $10B+ in Sales for Lilly Oral GLP-1 Alex Philippidis, GEN Edge, September 1, 2025 Touching Base Podcast Hosted by Corinna Singleman, PhD Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD Hosted on Acast. See acast.com/privacy for more information.","meta_description":"Novartis has agreed to license and develop Arrowhead Pharmaceuticals’ preclinical stage small interfering RNA (siRNA) therapy ARO-SNCA, a potential treatm…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1650,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/developing-new-therapies-through-partnership-electricity-and-immunotherapy/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/developing-new-therapies-through-partnership-electricity-and-immunotherapy.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}