{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Customized CRISPR for KJ, 10x and Illumina Lawsuits, Regeneron Bags 23andMe","slug":"customized-crispr-for-kj-10x-and-illumina-lawsuits-regeneron-bags-23andme","published_at":"2025-05-22T16:38:20+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/customized-crispr-for-kj-10x-and-illumina-lawsuits-regeneron-bags-23andme","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/customized-crispr-for-kj-10x-and-illumina-lawsuits-regeneron","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/682f3fb8fc865cdd04947ad2/media.mp3","summary":"A baby, named KJ, has become the first patient to be treated with a personalized CRISPR therapy to address a severe metabolic disorder. We discuss this story—one of the biggest science/medical stories from ASGCT 2025—and talk about the family and scientists at its center. In other news, laboratory-evolved CRISPR-associated bacterial transposases are being used to insert healthy genes into human cells. On the business front, 10x Genomics settles with Bruker and Vizgen while Illumina sues Element Biosciences for patent infringement. Also, trouble for Prime Medicine as the company pivots its pipeline and downsizes, and after months of speculation about its fate, 23andMe is acquired by Regeneron. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news.  Listed below are links to the GEN stories referenced in this episode of Touching Base ASGCT 2025: World’s First Patient Treated with Personalized CRISPR Therapy   By Fay Lin, PhD, GEN, May 15, 2025  EvoCAST Harnesses CRISPR-Linked Bacterial Transposases to Insert Genes Into Human Cells   GEN, May 18, 2025  eePASSIGE Engineers Gene-Sized Edits in Human Cells   GEN, June 10, 2024  Illumina Sues Element Biosciences, Alleging Infringement of Flow Cell, Imaging Patents   By Alex Philippidis, GEN Edge, May 18, 2025 10x Settles Bruker, Vizgen Patent Lawsuits   By Julianna LeMieux, PhD, and Alex Philippidis, GEN, May 18, 2025    Prime Medicine Chops 25% of Workforce, Pivots Pipeline as CEO Quits   By Alex Philippidis, GEN Edge, May 19, 2025  Regeneron to Acquire 23andMe with Winning $256M Bid   GEN, May 19, 2025  Hosted on Acast. See…","meta_description":"A baby, named KJ, has become the first patient to be treated with a personalized CRISPR therapy to address a severe metabolic disorder. We discuss th…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2494,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/customized-crispr-for-kj-10x-and-illumina-lawsuits-regeneron-bags-23andme/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/customized-crispr-for-kj-10x-and-illumina-lawsuits-regeneron-bags-23andme.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}