{"podcast":{"title":"Touching Base","slug":"touching-base-6714887","podcast_index_feed_id":6714887,"rss_url":"https://feeds.acast.com/public/shows/65736d39d32e730012c98919","website_url":"https://shows.acast.com/65736d39d32e730012c98919","image_url":"https://assets.pippa.io/shows/cover/1702062363830-62d389f5db6a973569dc75512134cd32.jpeg","author":"Genetic Engineering & Biotechnology News (GEN)","episode_count":55,"summary":"Touching Base is the dynamic podcast series from the editors of GEN ( Genetic Engineering & Biotechnology News ). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next. Hosted on Acast. See acast.com/privacy for more information.","last_synced_at":"2026-08-01T02:20:08.667530+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887"},"episode":{"title":"Bacteria 4D Simulation, Safer Large Gene Insertion, uniQure Roller Coaster","slug":"bacteria-4d-simulation-safer-large-gene-insertion-uniqure-roller-coaster","published_at":"2026-03-13T01:12:28+00:00","page_url":"https://stenobird.com/podcast/touching-base-6714887/bacteria-4d-simulation-safer-large-gene-insertion-uniqure-roller-coaster","show_page_url":"https://stenobird.com/podcast/touching-base-6714887","url":"https://shows.acast.com/touching-base/episodes/bacteria-4d-simulation-safer-large-gene-insertion-uniqure-ro","audio_url":"https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/69b33e2a6250eadca2f067e2/media.mp3","summary":"A new study from the J. Craig Venter Institute simulates the complete life cycle of a minimal bacterial cell in 4D space and time at nanoscale resolution. Meanwhile, in gene editing, a new technology has designed DNA donors that evade the immune system, allowing safer large gene insertion that is one step closer to scalable mutation-agnostic therapies. In brain diseases, researchers have found a novel blood-based biomarker that can predict a woman’s risk of developing dementia as many as 25 years before symptoms appear. Our episode rounds out with uniQure’s roller coaster stock, following Vinay Prasad, MD, and his second departure from the FDA.   Join GEN editors Corinna Singleman, PhD, Fay Lin, PhD, Uduak Thomas and Alex Philippidis for a discussion of the latest biotech and biopharma news.    Listed below are links to the GEN stories referenced in this episode of Touching Base :    Simulating Life: 4D Whole-Cell Model of a Minimal Bacterium GEN , March 9, 2026   Safer Large DNA Insertion Moves Genetic Medicine Toward Scalability By Fay Lin, PhD, GEN , March 11, 2026 Blood Biomarker Predicts Women’s Dementia Risk Up to 25 Years Early GEN , March 10, 2026 StockWatch: Under Fire from FDA, uniQure Stock Roller-Coasters By Alex Philippidis, GEN Edge , March 8, 2026 Touching Base Podcast   Hosted by Corinna Singleman, PhD    Behind the Breakthroughs   Hosted by Jonathan D. Grinstein, PhD  Hosted on Acast. See acast.com/privacy for more information.","meta_description":"A new study from the J. Craig Venter Institute simulates the complete life cycle of a minimal bacterial cell in 4D space and time at nanoscale resolution.…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2462,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/bacteria-4d-simulation-safer-large-gene-insertion-uniqure-roller-coaster/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/touching-base-6714887/bacteria-4d-simulation-safer-large-gene-insertion-uniqure-roller-coaster.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}