{"podcast":{"title":"This Week in Startups","slug":"this-week-in-startups","podcast_index_feed_id":788244,"rss_url":"https://anchor.fm/s/7c624c84/podcast/rss","website_url":"https://thisweekinstartups.com","image_url":"https://d3t3ozftmdmh3i.cloudfront.net/staging/podcast_uploaded_nologo/20768169/20768169-1702529323365-30a5ed5f170b.jpg","author":"Jason Calacanis","episode_count":1419,"summary":"Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/this-week-in-startups"},"episode":{"title":"5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286","slug":"5-000-tech-workers-laid-off-this-week-it-s-just-the-beginning-e2286","published_at":"2026-05-09T00:40:11+00:00","page_url":"https://stenobird.com/podcast/this-week-in-startups/5-000-tech-workers-laid-off-this-week-it-s-just-the-beginning-e2286","show_page_url":"https://stenobird.com/podcast/this-week-in-startups","url":"https://podcasters.spotify.com/pod/show/thisweekinstartups/episodes/5-000-Tech-Workers-Laid-Off-This-Week--Its-Just-The-Beginning---E2286-e3j407l","audio_url":"https://anchor.fm/s/7c624c84/podcast/play/119717557/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-4-9%2F423789474-44100-2-8026f827616c4.mp3","summary":"This Week In Startups is made possible by: IM8 Health - https://IM8health.com/TWIST Every - Every.io Sentry - https://Sentry.io/TWIST Banks don’t want to hand over their data to AI labs. So David Moscatelli built a $250,000 box that runs AI on-prem. He already has 1,600 pre-orders. On today’s episode of TWiST, Jason and Alex sit down with the Go Abacus founder and Yanez's Jose Caldera to unpack how regulated industries are getting AI without the cloud, why Bittensor subnet 54 is incentivizing miners to attack identity systems, and why Cloudflare just laid off 20% of its workforce in the same week it raised guidance. The show closes with Jason explaining what it means to build an AI-first startup, and how workers can derisk their future employment! Guest Links: Go Abacus Go1 direct link David Moscatelli on LinkedIn Yanez Bittensor Subnet 54 on TAOstats Jose Caldera on LinkedIn LAUNCH Links: Founder University Founder University Japan application portal News Links: Cloudflare lays off 20% of its staff Coinbase cuts 14% of its staff Block post on how it is rebuilding its company Block’s earnings, including its raised guidance Anthropic’s massive upcoming funding round WHOOP’s new on-demand clinicians Stripe Atlas’s growth Timestamps: 0:00 Introduction: Jason in Brooklyn, Knicks playoffs 2:30 Go Abacus joins: AI infrastructure for regulated industries 3:25 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 4:00 The Go1: 2,000-user on-prem AI appliance 7:04 Pricing the Go1: How far does $250,000 go? 7:24 1,600 orders and the hardware delivery challenge 10:14 Sentry - New users can get $240 in free credits when they go to https://sentry.io/twist…","meta_description":"This Week In Startups is made possible by: IM8 Health - https://IM8health.com/TWIST Every - Every.io Sentry - https://Sentry.io/TWIST Banks don’t want to…","key_points":[],"chapters":[],"topics":[],"duration_seconds":4320,"processing_state":"failed","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/this-week-in-startups/episodes/5-000-tech-workers-laid-off-this-week-it-s-just-the-beginning-e2286/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/this-week-in-startups/5-000-tech-workers-laid-off-this-week-it-s-just-the-beginning-e2286.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}