{"podcast":{"title":"This Week in Microbiology","slug":"this-week-in-microbiology-1045713","podcast_index_feed_id":1045713,"rss_url":"https://twimshow.libsyn.com/rss","website_url":"http://www.asm.org/twim/","image_url":"https://static.libsyn.com/p/assets/a/4/a/b/a4ab14edd084774e16c3140a3186d450/TWiM_2026-1400.jpg","author":"American Society for Microbiology","episode_count":360,"summary":"This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.","last_synced_at":"2026-07-19T06:19:00.683301+00:00","page_url":"https://stenobird.com/podcast/this-week-in-microbiology-1045713"},"episode":{"title":"343: Nucleotides to the Defense","slug":"343-nucleotides-to-the-defense","published_at":"2025-10-25T05:52:09+00:00","page_url":"https://stenobird.com/podcast/this-week-in-microbiology-1045713/343-nucleotides-to-the-defense","show_page_url":"https://stenobird.com/podcast/this-week-in-microbiology-1045713","url":"https://www.microbe.tv/twim/twim-343/","audio_url":"https://traffic.libsyn.com/secure/twimshow/TWiM343.mp3?dest-id=53322","summary":"TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Martin Become a patron of TWiM. Links for this episode: Decoy cyclic nucleotides in phage defense (Nature) CRISPR defense with nucleotides (Nature) A decoy defence molecule to set a trap for viruses (Nature) Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv","meta_description":"TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Marti…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2637,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/this-week-in-microbiology-1045713/episodes/343-nucleotides-to-the-defense/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/this-week-in-microbiology-1045713/343-nucleotides-to-the-defense.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}