{"podcast":{"title":"The Science of Age-less Living","slug":"the-science-of-age-less-living-7235688","podcast_index_feed_id":7235688,"rss_url":"https://media.rss.com/the-science-of-age-less-living/feed.xml","website_url":"https://rss.com/podcasts/the-science-of-age-less-living/","image_url":"https://media.rss.com/the-science-of-age-less-living/20251203_051216_dcfbba3c86faaedb3846ad2813128728.png","author":"Dr. Ethan Hausman-Marquis","episode_count":37,"summary":"Welcome to The Science of Age-Less Living ! Dr. Ethan Hausman-Marquis—logevity researcher, biohacker and founder of The Catalyst Clinic—shares his journey into the fields of aesthetics, regenerative medicine, and longevity science, and offers a look at what the future of aging may hold. From his early studies at UCLA to advanced work in genomics and molecular biology at L’École Normale Supérieure in Paris and a PhD at the Karolinska Institute in Stockholm, Dr. Ethan’s path has been guided by one goal: helping people live longer, healthier, and more vibrant lives. He is the author of Exploring the World of Peptides: From Basics to Breakthroughs and Peptide-Based Cancer Therapies: A New Frontier in Precision Medicine , and has contributed to several peer-reviewed publications on cutting-edge medical research. In this episode, Dr. Ethan reflects on his transition from academic research to clinical innovation at The Catalyst Clinic—with locations in London, New York, Amsterdam, and soon Zürich—and sets the stage for what’s to come in future episodes. Each week, The Science of Age-Less Living explores the molecular and cell biology of longevity—the evolving landscape of regenerative me…","last_synced_at":"2026-06-25T22:18:53.982257+00:00","page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688"},"episode":{"title":"Aging Isn't Wear and Tear—It's a Timing Problem: The Age-less Clock and Restoring Biological Rhythm","slug":"aging-isn-t-wear-and-tear-it-s-a-timing-problem-the-age-less-clock-and-restoring-biological-rhythm","published_at":"2026-01-30T21:09:18+00:00","page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688/aging-isn-t-wear-and-tear-it-s-a-timing-problem-the-age-less-clock-and-restoring-biological-rhythm","show_page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688","url":"https://rss.com/podcasts/the-science-of-age-less-living/2508028","audio_url":"https://content.rss.com/episodes/319089/2508028/the-science-of-age-less-living/2026_01_30_21_08_30_f248fb8f-6ec7-4711-a4f8-8684bfbd0606.mp3","summary":"In this episode of The Science of Age-less Living , Dr. Ethan argues that aging is not primarily about accumulated damage (oxidative stress, inflammation, telomere shortening), but a loss of timing and synchronization in the body’s biological clocks. The master clock (SCN in the brain) and peripheral clocks in organs coordinate hormones, gene expression, metabolism, repair, and immunity in precise rhythms—strong and harmonious in youth, but increasingly damped and desynchronized with age. This breakdown causes inefficient repair, unchecked inflammation, and rapid functional decline, explaining why organs age at different rates and why short-term sleep loss accelerates aging markers faster than expected. Sleep is highlighted as the key synchronizer (via melatonin, growth hormone pulses, etc.), while continuous, non-rhythmic interventions (daily NAD+ boosters, peptides, supplements) often backfire by flattening natural oscillations and worsening discord. The solution: prioritize rhythm restoration through optimized sleep, light-dark alignment, and pulsed, cyclical, personalized protocols that respect the body’s innate timing rather than brute-force constant stimulation. By re-synchronizing the “orchestra,” vitality and healthy lifespan can be meaningfully extended.","meta_description":"In this episode of The Science of Age-less Living , Dr. Ethan argues that aging is not primarily about accumulated damage (oxidative stress, inflammation,…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1533,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-science-of-age-less-living-7235688/episodes/aging-isn-t-wear-and-tear-it-s-a-timing-problem-the-age-less-clock-and-restoring-biological-rhythm/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688/aging-isn-t-wear-and-tear-it-s-a-timing-problem-the-age-less-clock-and-restoring-biological-rhythm.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}