{"podcast":{"title":"The Science of Age-less Living","slug":"the-science-of-age-less-living-7235688","podcast_index_feed_id":7235688,"rss_url":"https://media.rss.com/the-science-of-age-less-living/feed.xml","website_url":"https://rss.com/podcasts/the-science-of-age-less-living/","image_url":"https://media.rss.com/the-science-of-age-less-living/20251203_051216_dcfbba3c86faaedb3846ad2813128728.png","author":"Dr. Ethan Hausman-Marquis","episode_count":37,"summary":"Welcome to The Science of Age-Less Living ! Dr. Ethan Hausman-Marquis—logevity researcher, biohacker and founder of The Catalyst Clinic—shares his journey into the fields of aesthetics, regenerative medicine, and longevity science, and offers a look at what the future of aging may hold. From his early studies at UCLA to advanced work in genomics and molecular biology at L’École Normale Supérieure in Paris and a PhD at the Karolinska Institute in Stockholm, Dr. Ethan’s path has been guided by one goal: helping people live longer, healthier, and more vibrant lives. He is the author of Exploring the World of Peptides: From Basics to Breakthroughs and Peptide-Based Cancer Therapies: A New Frontier in Precision Medicine , and has contributed to several peer-reviewed publications on cutting-edge medical research. In this episode, Dr. Ethan reflects on his transition from academic research to clinical innovation at The Catalyst Clinic—with locations in London, New York, Amsterdam, and soon Zürich—and sets the stage for what’s to come in future episodes. Each week, The Science of Age-Less Living explores the molecular and cell biology of longevity—the evolving landscape of regenerative me…","last_synced_at":"2026-06-25T22:18:53.982257+00:00","page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688"},"episode":{"title":"Age-less Revolution: Why We Age — From DNA Damage to Cellular Energy — and How Longevity Medicine Is Rewriting the Rules","slug":"age-less-revolution-why-we-age-from-dna-damage-to-cellular-energy-and-how-longevity-medicine-is-rewriting-the-rules","published_at":"2025-12-29T21:23:35+00:00","page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688/age-less-revolution-why-we-age-from-dna-damage-to-cellular-energy-and-how-longevity-medicine-is-rewriting-the-rules","show_page_url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688","url":"https://rss.com/podcasts/the-science-of-age-less-living/2419146","audio_url":"https://content.rss.com/episodes/319089/2419146/the-science-of-age-less-living/2025_12_29_21_23_00_8d35a13c-3133-4cf7-9796-049536dd2cea.mp3","summary":"Why do we age? Is it simply the passage of time — or something far more precise, and far more modifiable? In this episode of The Science of Age-less Living , Dr. Ethan Hausman-Marquis takes you deep into the real biology of aging, revealing why growing older is not an inevitable countdown, but a consequence of accumulated cellular damage and declining repair capacity. You’ll learn why aging is best understood as a systems-level failure — a breakdown in information, energy, and repair — rather than a single disease. We explore how DNA damage accumulates over time, why epigenetic regulation drifts and causes identical twins to age differently, and how loss of proteostasis leads to protein misfolding and neurodegenerative disease. The episode then zooms into the cell’s power plants: mitochondria. You’ll discover why mitochondrial dysfunction may be the true biological clock of aging, how redox imbalance and failed mitophagy turn cells into energy-starved “zombie” states, and why restoring mitochondrial health has such wide-ranging effects on longevity. We break down the critical role of NAD⁺ — the cell’s universal energy currency — explaining how its age-related decline impairs DNA repair, silences longevity genes, and accelerates cellular dysfunction, and why NAD⁺ restoration has become a cornerstone of modern longevity medicine. Finally, we demystify peptides. Far from hype or bro-science, peptides are revealed as precision signaling molecules that restore lost cellular communication, gently reminding cells how to behave the way they did in youth — supporting tissue repair, neuroplasticity, immune balance, and healthy growth hormone signaling. This episode reframes aging as a treatable, measurable process — not an unavoidable fate. By the end, you’ll walk away with a cl…","meta_description":"Why do we age? Is it simply the passage of time — or something far more precise, and far more modifiable? In this episode of The Science of Age-less Livin…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1712,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-science-of-age-less-living-7235688/episodes/age-less-revolution-why-we-age-from-dna-damage-to-cellular-energy-and-how-longevity-medicine-is-rewriting-the-rules/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-science-of-age-less-living-7235688/age-less-revolution-why-we-age-from-dna-damage-to-cellular-energy-and-how-longevity-medicine-is-rewriting-the-rules.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}