{"podcast":{"title":"The Readout Loud","slug":"the-readout-loud-1134305","podcast_index_feed_id":1134305,"rss_url":"https://feeds.megaphone.fm/thereadoutloud","website_url":"https://soundcloud.com/readout-loud","image_url":"https://megaphone.imgix.net/podcasts/2700b5c2-6d26-11ee-87eb-1f9099431c15/image/517bb4949d560305bb39448edbb32d7a.jpg?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"STAT","episode_count":414,"summary":"STAT’s weekly biotech podcast, breaking down the latest news, digging deep into industry goings-on, and giving you a preview of the week to come.","last_synced_at":"2026-07-17T08:20:19.054206+00:00","page_url":"https://stenobird.com/podcast/the-readout-loud-1134305"},"episode":{"title":"409: Predicting biotech clinical trials & a new Alzheimer's drug controversy","slug":"409-predicting-biotech-clinical-trials-a-new-alzheimer-s-drug-controversy","published_at":"2026-07-16T20:01:00+00:00","page_url":"https://stenobird.com/podcast/the-readout-loud-1134305/409-predicting-biotech-clinical-trials-a-new-alzheimer-s-drug-controversy","show_page_url":"https://stenobird.com/podcast/the-readout-loud-1134305","url":"https://traffic.megaphone.fm/TTSAA9068866669.mp3","audio_url":"https://traffic.megaphone.fm/TTSAA9068866669.mp3","summary":"On this week’s episode of \"The Readout LOUD\": The Kalshi prediction markets are coming for biotech, plus the controversy over an experimental Alzheimer’s disease treatment from Biogen. Kalshi, the maker of prediction markets, announced this week that it is expanding into biotech. Soon, you’ll be able to make bets on the outcomes of clinical trials and FDA drug reviews. Is that a good thing? We’ll discuss the issues with Jonathan Kimmelman, a bioethicist at McGill University who has researched prediction in clinical trials. We also chat about Biogen and its tau-lowering drug for Alzheimer’s. A mid-stage clinical trial presented this week showed the drug reduced levels of the tau protein and slowed the rate of cognitive decline in patients. But the data also raised a lot of questions that left experts and investors debating the drug’s future.","meta_description":"On this week’s episode of \"The Readout LOUD\": The Kalshi prediction markets are coming for biotech, plus the controversy over an experimental Alzheimer’s…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2132,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-readout-loud-1134305/episodes/409-predicting-biotech-clinical-trials-a-new-alzheimer-s-drug-controversy/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-readout-loud-1134305/409-predicting-biotech-clinical-trials-a-new-alzheimer-s-drug-controversy.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}