{"podcast":{"title":"The Human Upgrade: Biohacking for Longevity & Performance","slug":"the-human-upgrade-biohacking-for-longevity-performance-1031629","podcast_index_feed_id":1031629,"rss_url":"https://rss.art19.com/human-upgrade","website_url":"https://daveasprey.com/category/podcasts/","image_url":"https://content.production.cdn.art19.com/images/8a/08/50/8c/8a08508c-e0b0-4761-8eeb-e26d8dcc9a11/c8b0e53403b0f567938e72d32ba01ad021e82e8517b3c2e7a9d8367fcb5253a0472522241e7b60d9298bddc2eba33b5a9f5ac4df0023690ae76b17d3dad50d33.jpeg","author":"Dave Asprey","episode_count":1558,"summary":"For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.","last_synced_at":"2026-07-18T04:21:16.572334+00:00","page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629"},"episode":{"title":"It's Weird, But It Turns On Your Body's Anti-Aging Switch Fast : 1487","slug":"it-s-weird-but-it-turns-on-your-body-s-anti-aging-switch-fast-1487","published_at":"2026-06-21T08:30:00+00:00","page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/it-s-weird-but-it-turns-on-your-body-s-anti-aging-switch-fast-1487","show_page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629","url":"https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/3342c14f-5601-4851-9d57-c1db55e7388a.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0","audio_url":"https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/3342c14f-5601-4851-9d57-c1db55e7388a.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0","summary":"Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/ Try Suppgrade Labs: https://shopsuppgradelabs.com/ If you're eating clean, taking the right supplements, and still feel exhausted and mentally foggy - the problem isn't your protocol. Your body has a built-in cellular cleanup system that determines whether any of those inputs actually work, and right now it's almost certainly switched off. In this video, I break down what that system is, how chronic stress and all-day eating suppress it without you ever feeling it, and the specific compounds that flip the longevity switch back on through independent biological pathways that nothing else touches. Thank you to our sponsors! ECHO Water | Go to  http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. EMR-Tek |  https://www.emr-tek.com/DAVE  and use code DAVE for 40% off. iRestore | Reverse hair loss at  www.irestore.com/DAVE  and get exclusive savings on the iRestore Elite, use code DAVE Timestamps: 0:00 – The Longevity Switch 0:47 – Why Mitochondria Matter 2:28 – What Mitophagy Is 2:46 – How Mitophagy Works 4:18 – What Shuts It Off 8:54 – The Damage Compounds 9:22 – How to Turn It Back On 10:31 – Signal 1: Fasting 11:48 – Signal 2: Exercise (REHIT) 12:30 – Signal 3: Cold Exposure 13:22 – Signal 4: NAD+ 14:29 – Signal 5: Urolithin A and Spermidine Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgr…","meta_description":"Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/ Try Suppgrade Labs: https://shopsuppgradelabs.com/ If you're eatin…","key_points":[],"chapters":[],"topics":[],"duration_seconds":934,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/it-s-weird-but-it-turns-on-your-body-s-anti-aging-switch-fast-1487/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/it-s-weird-but-it-turns-on-your-body-s-anti-aging-switch-fast-1487.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}