{"podcast":{"title":"The Human Upgrade: Biohacking for Longevity & Performance","slug":"the-human-upgrade-biohacking-for-longevity-performance-1031629","podcast_index_feed_id":1031629,"rss_url":"https://rss.art19.com/human-upgrade","website_url":"https://daveasprey.com/category/podcasts/","image_url":"https://content.production.cdn.art19.com/images/8a/08/50/8c/8a08508c-e0b0-4761-8eeb-e26d8dcc9a11/c8b0e53403b0f567938e72d32ba01ad021e82e8517b3c2e7a9d8367fcb5253a0472522241e7b60d9298bddc2eba33b5a9f5ac4df0023690ae76b17d3dad50d33.jpeg","author":"Dave Asprey","episode_count":1558,"summary":"For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.","last_synced_at":"2026-07-18T04:21:16.572334+00:00","page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629"},"episode":{"title":"Here's Why Your Supplements Don't Seem To Work | Nayan Patel  : 1502","slug":"here-s-why-your-supplements-don-t-seem-to-work-nayan-patel-1502","published_at":"2026-07-16T08:30:00+00:00","page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/here-s-why-your-supplements-don-t-seem-to-work-nayan-patel-1502","show_page_url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629","url":"https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/559728a9-55f8-49b3-b6aa-3db530c506f1.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0","audio_url":"https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/559728a9-55f8-49b3-b6aa-3db530c506f1.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0","summary":"Why Oral and IV Glutathione Never Actually Reach Your Cells (The Delivery Breakthrough Changing Everything)  Most of the supplements you're taking aren't failing you, they're failing to ever reach the cells that need them, and almost nobody selling them wants you to know that. This episode hands you the delivery breakthrough that actually gets it there.  Use code DAVE for a discount at aurowellness.com/dave   Host Dave Asprey sits down with Dr. Nayan Patel, a pharmacist, researcher, and founder of Auro Wellness, whose work centers on solving one of biohacking's most stubborn problems: getting nutrients past the bloodstream and into the cells that actually need them. He holds 14 patents in delivery technology, partners in the high-end longevity clinic Unlimited Life, and has spent over two decades studying glutathione, the master antioxidant his own research helped bring into modern biohacking.  Dave and Dr. Patel break down a 2011 University of Texas study showing that oral and liposomal glutathione are completely broken down into raw amino acids before absorption, meaning none of it reaches the bloodstream as glutathione, a pattern that holds true even for IV administration. They dig into new brain-imaging research showing topical glutathione crossing into neural tissue within 20 minutes, why senescent \"zombie cells\" may be directly tied to glutathione shortfalls, and why NAD, despite its reputation as the ultimate longevity molecule, is actually dependent on glutathione to do its job. They also cover the real purity ceiling on GHK-copper peptides, safe upper limits for glycine and NAC before they start working against you, a topical alcohol protocol that clears acetaldehyde without triggering a breathalyzer, and why oxidative stress from GLP-1 use…","meta_description":"Why Oral and IV Glutathione Never Actually Reach Your Cells (The Delivery Breakthrough Changing Everything) Most of the supplements you're taking ar…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3513,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/here-s-why-your-supplements-don-t-seem-to-work-nayan-patel-1502/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/here-s-why-your-supplements-don-t-seem-to-work-nayan-patel-1502.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}