{"podcast":{"title":"The Energy Code","slug":"the-energy-code-2136601","podcast_index_feed_id":2136601,"rss_url":"https://feed.podbean.com/theenergycode/feed.xml","website_url":"https://feed.podbean.com/theenergycode/feed.xml","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/10635338/Energy_Code_Apple_Podcast_Cover_Final.jpg","author":"Dr. Mike Belkowski","episode_count":369,"summary":"The Red Light Report podcast is your number one source for all things red light therapy, hosted by Dr. Mike Belkowski, the founder and CEO of BioLight. Dr. Belkowski discusses the many health-related benefits of properly utilizing red light therapy and explores the best and most recent research related to photobiomodulation (ie, red light therapy). He will also be interviewing some of the most interesting and respected health, wellness, longevity and biohacking experts from around the world. Want to learn even more about red light therapy? Check out these sources: www.biolight.shop – Instagram @biolight.shop – YouTube BioLight","last_synced_at":"2026-07-23T22:20:31.206492+00:00","page_url":"https://stenobird.com/podcast/the-energy-code-2136601"},"episode":{"title":"The Brain’s Redox Crisis: NAD, Mitochondria, and the Next Wave of Neuropsychiatric Treatment","slug":"the-brain-s-redox-crisis-nad-mitochondria-and-the-next-wave-of-neuropsychiatric-treatment","published_at":"2026-04-24T15:26:03+00:00","page_url":"https://stenobird.com/podcast/the-energy-code-2136601/the-brain-s-redox-crisis-nad-mitochondria-and-the-next-wave-of-neuropsychiatric-treatment","show_page_url":"https://stenobird.com/podcast/the-energy-code-2136601","url":"https://theenergycode.podbean.com/e/the-brain-s-redox-crisis-nad-mitochondria-and-the-next-wave-of-neuropsychiatric-treatment/","audio_url":"https://mcdn.podbean.com/mf/web/fewvmznt4upi7iwj/redox_mixdown.mp3","summary":"Neuropsychiatric and neurodegenerative diseases may share a common underlying pathology: a breakdown in the brain's redox balance. This deep dive explores how disruptions in the NAD+/NADH ratio drive mitochondrial failure and inflammation across diverse diagnoses.","meta_description":"Explore the link between NAD+ imbalance, mitochondrial dysfunction, and neuropsychiatric disorders like Alzheimer's and Schizophrenia.","key_points":["Main idea: Redox dysregulation, specifically the NAD+/NADH ratio, acts as a shared organizing principle for both neurodegeneration and psychiatric illness","Failure mode: Raising NAD levels in the blood does not guarantee the correction of compartmentalized redox failure within specific brain cells","Practical takeaway: Ketogenic therapy may offer benefits beyond alternative fuel by actively modulating the NAD+/NADH redox state","Critical bottleneck: The field lacks robust in vivo biomarkers to prove that redox-based therapies are actually engaging their targets in the brain","Future direction: Effective treatment must shift from broad supplementation to mechanism-driven, precision interventions based on metabolic signatures"],"chapters":[{"start_ms":60000,"title":"Redox Failure as a Shared Pathology","summary":"An introduction to the thesis that brain disorders are fundamentally issues of redox and bioenergetic failure."},{"start_ms":120000,"title":"The NAD+/NADH Ratio","summary":"Defining redox balance through the lens of metabolic control and mitochondrial efficiency."},{"start_ms":240000,"title":"Beyond Protein Aggregation","summary":"Why targeting amyloid and tau has failed and why we must look toward mitochondrial stress."},{"start_ms":300000,"title":"Psychiatric Implications","summary":"How schizophrenia and bipolar disorder exhibit similar energetic vulnerabilities to neurodegenerative diseases."},{"start_ms":360000,"title":"Targeting NAD+","summary":"The potential and the specific molecular importance of NAD in restoring cellular function."},{"start_ms":480000,"title":"The Compartmentalization Problem","summary":"The challenge of ensuring therapies reach the cytosol, mitochondria, and nucleus effectively."},{"start_ms":540000,"title":"The Need for Biomarkers","summary":"Why measurement and target engagement are more critical to the field than new supplements."},{"start_ms":600000,"title":"Ketogenic Redox Modulation","summary":"How ketogenic interventions influence the redox state and improve metabolic flexibility."}],"topics":["Neuropsychiatry","Mitochondrial Dysfunction","NAD+","Redox Signaling","Alzheimer's Disease","Schizophrenia","Ketogenic Therapy","Bioenergetics","Biomarker Development"],"duration_seconds":1128,"processing_state":"processed","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-energy-code-2136601/episodes/the-brain-s-redox-crisis-nad-mitochondria-and-the-next-wave-of-neuropsychiatric-treatment/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-energy-code-2136601/the-brain-s-redox-crisis-nad-mitochondria-and-the-next-wave-of-neuropsychiatric-treatment.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}