{"podcast":{"title":"The Bio Report","slug":"the-bio-report-1092382","podcast_index_feed_id":1092382,"rss_url":"https://feed.podbean.com/thebioreport/feed.xml","website_url":"https://thebioreport.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/15149796/BRlogo_znb5nt.jpg","author":"Levine Media Group","episode_count":615,"summary":"The Bio Report podcast, hosted by award-winning journalist Daniel Levine, focuses on the intersection of biotechnology with business, science, and policy.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/the-bio-report-1092382"},"episode":{"title":"Tuning, Rather than Blocking, Immunity in IBD","slug":"tuning-rather-than-blocking-immunity-in-ibd","published_at":"2026-04-15T07:00:00+00:00","page_url":"https://stenobird.com/podcast/the-bio-report-1092382/tuning-rather-than-blocking-immunity-in-ibd","show_page_url":"https://stenobird.com/podcast/the-bio-report-1092382","url":"https://thebioreport.podbean.com/e/tuning-rather-than-blocking-immunity-in-ibd/","audio_url":"https://mcdn.podbean.com/mf/web/bwwayzd9jc462bey/BR-Marc_de_Garidel_-4-15-26b79ww.mp3","summary":"The treatment of inflammatory bowel disease currently relies on immunosuppressive therapies that often lose effectiveness, carry infection risks, and drive high treatment cycling. Abivax is betting that fine-tuning, rather than suppressing, the immune system can reshape the treatment paradigm in IBD. Marc de Garidel, CEO of Abivax, discusses how a once-failed HIV candidate evolved into a late‑stage oral IBD therapy that may deliver durable remission, how it acts upstream of key inflammatory pathways, and its potential in a crowded but still underserved IBD market.","meta_description":"The treatment of inflammatory bowel disease currently relies on immunosuppressive therapies that often lose effectiveness, carry infection risks, and driv…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2147,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-bio-report-1092382/episodes/tuning-rather-than-blocking-immunity-in-ibd/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-bio-report-1092382/tuning-rather-than-blocking-immunity-in-ibd.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}