{"podcast":{"title":"The Bio Report","slug":"the-bio-report-1092382","podcast_index_feed_id":1092382,"rss_url":"https://feed.podbean.com/thebioreport/feed.xml","website_url":"https://thebioreport.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/15149796/BRlogo_znb5nt.jpg","author":"Levine Media Group","episode_count":615,"summary":"The Bio Report podcast, hosted by award-winning journalist Daniel Levine, focuses on the intersection of biotechnology with business, science, and policy.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/the-bio-report-1092382"},"episode":{"title":"Reprogramming T Cells to Cross the Brain’s Border","slug":"reprogramming-t-cells-to-cross-the-brain-s-border","published_at":"2026-02-04T08:00:00+00:00","page_url":"https://stenobird.com/podcast/the-bio-report-1092382/reprogramming-t-cells-to-cross-the-brain-s-border","show_page_url":"https://stenobird.com/podcast/the-bio-report-1092382","url":"https://thebioreport.podbean.com/e/reprogramming-t-cells-to-cross-the-brain-s-border/","audio_url":"https://mcdn.podbean.com/mf/web/fvvwqijjvj657deu/BR-Michael_Roberts_-_2-4-26b4qpw.mp3","summary":"One of the challenges of treating brain tumors is delivering potent biologic therapies across the blood-brain barrier. Adaptin Bio has developed platform technology that harnesses a patient’s own T cells to transport bispecific therapeutic payloads across the blood-brain barrier and into other targeted tissue with an initial focus on treating glioblastoma. We spoke to Michael Roberts, co-founder and CEO of Adaptin Bio, about the unmet need in glioblastoma, the limitations of current blood-brain barrier–crossing strategies, and how the company’s platform seeks to change the treatment paradigm by using patient-derived T cells as delivery vehicles for targeted biologics.","meta_description":"One of the challenges of treating brain tumors is delivering potent biologic therapies across the blood-brain barrier. Adaptin Bio has developed platform…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2327,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-bio-report-1092382/episodes/reprogramming-t-cells-to-cross-the-brain-s-border/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-bio-report-1092382/reprogramming-t-cells-to-cross-the-brain-s-border.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}