{"podcast":{"title":"The Bio Report","slug":"the-bio-report-1092382","podcast_index_feed_id":1092382,"rss_url":"https://feed.podbean.com/thebioreport/feed.xml","website_url":"https://thebioreport.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/15149796/BRlogo_znb5nt.jpg","author":"Levine Media Group","episode_count":615,"summary":"The Bio Report podcast, hosted by award-winning journalist Daniel Levine, focuses on the intersection of biotechnology with business, science, and policy.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/the-bio-report-1092382"},"episode":{"title":"Developing an Alternative to Opioids for Post-Surgical Pain","slug":"developing-an-alternative-to-opioids-for-post-surgical-pain","published_at":"2025-12-24T08:00:00+00:00","page_url":"https://stenobird.com/podcast/the-bio-report-1092382/developing-an-alternative-to-opioids-for-post-surgical-pain","show_page_url":"https://stenobird.com/podcast/the-bio-report-1092382","url":"https://thebioreport.podbean.com/e/developing-an-alternative-to-opioids-for-post-surgical-pain/","audio_url":"https://mcdn.podbean.com/mf/web/6frtmaihbwbnqwn7/BR-Adam_Gridley_-_Final_12-24-258xb7g.mp3","summary":"The approach to post-surgical pain relief has relied on short-duration treatments and notably opioids. That’s led to the associated risks of dependence and abuse, prolonged hospitalizations, and slower recoveries. Allay Therapeutics is developing an alternative to opioids to treat post-surgical pain with an initial focus on knee replacement surgeries. Allay’s guitar pick-sized polymer is implanted during surgical procedures and it releases the analgesic bupivacaine as it dissolves over 30 days. We spoke to Adam Gridley, CEO of Allay Therapeutics, about post-surgical pain, the need for alternatives to opioids; and the company’s implanted, extended-release analgesic.","meta_description":"The approach to post-surgical pain relief has relied on short-duration treatments and notably opioids. That’s led to the associated risks of dependence an…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1547,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/the-bio-report-1092382/episodes/developing-an-alternative-to-opioids-for-post-surgical-pain/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/the-bio-report-1092382/developing-an-alternative-to-opioids-for-post-surgical-pain.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}