{"podcast":{"title":"Taking Control Of Your Diabetes® - The Podcast!","slug":"taking-control-of-your-diabetes-the-podcast-5259147","podcast_index_feed_id":5259147,"rss_url":"https://feeds.transistor.fm/tcoyd-the-podcast","website_url":"https://tcoydthepodcast.transistor.fm/","image_url":"https://img.transistorcdn.com/FuflZXvHzDpbO46c4EDfqb5UgqJAkK_cbSPCV88EGM0/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzI5MzMzLzE2OTcw/NTc3NjItYXJ0d29y/ay5qcGc.jpg","author":"Taking Control Of Your Diabetes®","episode_count":101,"summary":"Welcome to Taking Control Of Your Diabetes® - The Podcast, an edutaining show all about highs and lows of living with diabetes. Hosted by Dr. Steve Edelman and Dr. Jeremy Pettus, both endocrinologists who have been living with diabetes themselves since they were 15, we’re discussing the important topics that people living with diabetes need to know—and no topic is off-limits. From the latest advancements in diabetes medications and devices, to interviews with some of the best minds in diabetes, to personal stories about the ups and downs of dealing with this condition 24/7, we’re tackling what it means to live with diabetes in modern times. And we promise to make you laugh along the way, because sometimes we just need to laugh at the craziness that comes with living with diabetes. Tune in for a new episode on the last Monday of every month! Like what you hear and want to help us grow? Please rate and review this podcast so we can reach more people living with diabetes! VISIT: tcoyd.org | FOLLOW: tcoyd.org/contact | EMAIL: podcast@tcoyd.org APPLE PODCAST RATING: 4.9/🌟🌟🌟🌟🌟","last_synced_at":"2026-06-15T12:19:15.881438+00:00","page_url":"https://stenobird.com/podcast/taking-control-of-your-diabetes-the-podcast-5259147"},"episode":{"title":"Diabetes Cure with AAV Gene Therapy? Let's talk with Dr. Fraser Wright","slug":"diabetes-cure-with-aav-gene-therapy-let-s-talk-with-dr-fraser-wright","published_at":"2025-10-28T17:40:45+00:00","page_url":"https://stenobird.com/podcast/taking-control-of-your-diabetes-the-podcast-5259147/diabetes-cure-with-aav-gene-therapy-let-s-talk-with-dr-fraser-wright","show_page_url":"https://stenobird.com/podcast/taking-control-of-your-diabetes-the-podcast-5259147","url":"https://tcoydthepodcast.transistor.fm/86","audio_url":"https://media.transistor.fm/6b8f0669/949fd2d6.mp3","summary":"Gene therapy isn’t science fiction anymore , it’s becoming one of the most exciting frontiers in diabetes care. In this episode, Dr. Jeremy Pettus and Dr. Steve Edelman sit down with Dr. Fraser Wright, career gene therapist and Co-Founder/Chief Gene Therapy Officer at Kriya Therapeutics, to explore how gene therapy could one day help the body make its own insulin . Together, they unpack what gene therapy actually is, Dr. P’s involvement as a medical consultant for Kriya Therapeutics, how AAV (adeno-associated virus) vectors work, and what makes this “one-and-done” approach so different from traditional treatments . From success stories in blindness and hemophilia to emerging type 1 diabetes studies, the trio breaks down the science, the safety, and the hope behind this revolutionary research. You’ll learn how gene therapy has moved from rare diseases to more common ones, why the first human trials in diabetes are on the horizon, and what and what this could mean for long-term blood sugar control and independence from injections. Key Topics: Gene Therapy 101: How gene therapy differs from protein-based drugs like insulin, and why AAV vectors act as safe, engineered delivery vehicles rather than infectious viruses. Why AAV, Why Now: Seven FDA-approved AAV-based therapies have proven the potential of long-term, single-dose treatments. From Eyes to Endocrine: Lessons learned from retinal gene therapy are now guiding approaches to metabolic conditions like diabetes. The Type 1 Diabetes Approach: A muscle-targeted program aims to help the body naturally produce insulin and stabilize blood sugar levels. Control and Safety: Built-in glucose sensing and the ability to turn off gene expression ensure precision and reversibility. Real-World Considerations: How exercise, treatment…","meta_description":"Gene therapy isn’t science fiction anymore , it’s becoming one of the most exciting frontiers in diabetes care. In this episode, Dr. Jeremy Pettus and Dr.…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2081,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/taking-control-of-your-diabetes-the-podcast-5259147/episodes/diabetes-cure-with-aav-gene-therapy-let-s-talk-with-dr-fraser-wright/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/taking-control-of-your-diabetes-the-podcast-5259147/diabetes-cure-with-aav-gene-therapy-let-s-talk-with-dr-fraser-wright.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}