{"podcast":{"title":"Stuff Your Doctor Should Know","slug":"stuff-your-doctor-should-know-1049977","podcast_index_feed_id":1049977,"rss_url":"https://api.substack.com/feed/podcast/2173528.rss","website_url":"https://healthygutgirl.substack.com/podcast","image_url":"https://substackcdn.com/feed/podcast/2173528/3bdcbafac5544001af14e86c494b01ce.jpg","author":"\"Prescribing Knowledge Beyond Prescriptions: Tune into the 'Stuff Your Doctor Should Know' Podcast – Your Rx for Health Wisdom!\"","episode_count":288,"summary":"Your go-to for gut and hormone health. The Estrogen Dominance Support Group archives now live here, uncensored, uncaged, and packed with the good stuff Facebook won’t let us say.","last_synced_at":"2026-06-27T06:18:02.022733+00:00","page_url":"https://stenobird.com/podcast/stuff-your-doctor-should-know-1049977"},"episode":{"title":"#281 When “Healthy” Makes You Feel Awful:","slug":"281-when-healthy-makes-you-feel-awful","published_at":"2026-04-10T19:39:50+00:00","page_url":"https://stenobird.com/podcast/stuff-your-doctor-should-know-1049977/281-when-healthy-makes-you-feel-awful","show_page_url":"https://stenobird.com/podcast/stuff-your-doctor-should-know-1049977","url":"https://healthygutgirl.substack.com/p/when-healthy-makes-you-feel-awful","audio_url":"https://api.substack.com/feed/podcast/193745667/1ac4bcb02e63e31db7adec0eaaa54496.mp3","summary":"In this episode, Kitty is joined by Dr. Tyler Panzner , a pharmacologist who specializes in how nutrients, supplements, and hormones actually work in the body. Together, they unpack a question so many people are quietly asking: Why do supplements and hormones help some people—but make others feel worse? Dr. Panzner explains, in plain language, how supplements often have multiple effects at once , why genetics can change how your body responds, and why feeling “wired,” anxious, groggy, or overstimulated isn’t random—or a sign that you’re broken. They explore common examples like quercetin, melatonin, vitamin D, and estrogen, showing how the same intervention can be supportive for one person and problematic for another. The conversation also dives into hormone therapy headlines, including the removal of the FDA black box warning on estrogen, and why “safe for everyone” is never a biologically honest statement. Kitty and Dr. Panzner discuss estrogen metabolism, detox pathways, genetics, and the growing gap between real-world patients and one-size-fits-all medical advice. This episode is about nuance, personalization, and self-understanding —not fear, dogma, or extremes. If you’ve ever felt confused by conflicting health advice, overwhelmed by supplements, or frustrated that “doing everything right” still isn’t working, this conversation will help you make sense of why. Topics discussed: * Why the same supplement can feel amazing for one person… and awful for another (it’s doing more than you think) * “Hidden side effects” of supplements: the part nobody talks about (the iceberg under the water) * Quercetin example: great for allergies for some, but can make others feel wired, anxious, or “amped up” * Genes 101 in plain English: “variant” vs “mutation” and why it doesn’t m…","meta_description":"In this episode, Kitty is joined by Dr. Tyler Panzner , a pharmacologist who specializes in how nutrients, supplements, and hormones actually work in the…","key_points":[],"chapters":[],"topics":[],"duration_seconds":5348,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/stuff-your-doctor-should-know-1049977/episodes/281-when-healthy-makes-you-feel-awful/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/stuff-your-doctor-should-know-1049977/281-when-healthy-makes-you-feel-awful.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}