{"podcast":{"title":"Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas","slug":"sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522","podcast_index_feed_id":444522,"rss_url":"https://rss.libsyn.com/shows/604590/destinations/5264190.xml","website_url":"https://www.preposterousuniverse.com/podcast/","image_url":"https://static.libsyn.com/p/assets/b/0/6/d/b06d098337897af116c3140a3186d450/21d641ef836c48dff270cbede4360d187bdd6c56cb126be7d6f51078db34d4675527fa72e13c86bb573ec42c5d4fc493e18e7d95fec734ec77168fc379baefcf.jpeg","author":"Sean Carroll","episode_count":436,"summary":"Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you've come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.","last_synced_at":"2026-07-21T04:17:06.610110+00:00","page_url":"https://stenobird.com/podcast/sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522"},"episode":{"title":"357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics","slug":"357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics","published_at":"2026-06-15T11:15:00+00:00","page_url":"https://stenobird.com/podcast/sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522/357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics","show_page_url":"https://stenobird.com/podcast/sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522","url":"https://www.preposterousuniverse.com/podcast/2026/06/15/357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics/","audio_url":"https://dts.podtrac.com/redirect.mp3/pscrb.fm/rss/p/traffic.libsyn.com/secure/1d1ac211-8392-45fe-82db-99fa7f77076e/Jeff_Coller.mp3?dest-id=5264190","summary":"Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between the DNA where it is stored to the ribosome where it is used to produce proteins. RNA may even have been the first molecule to kick-start the origin of life. Today, scientists are learning how to manipulate mRNA to cure and prevent diseases, whether through vaccination or literally editing one's DNA. Jeff Coller explains how it all works and how mRNA is revolutionizing medicine as we know it. Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/06/15/357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics/ Support Mindscape on Patreon . Jeff Coller received his Ph.D. in cell and molecular biology from the University of Wisconsin-Madison. He is currently Bloomberg Distinguished Professor of Biomedical Engineering and Director of the RNA Innovation Center at Johns Hopkins University. He is co-founder of Tevard Biosciences and the Alliance for mRNA Medicines, and leads the REPAIRx consortium. He is a fellow of the American Association for the Advancement of Science. Web site Johns Hopkins web page Google Scholar publications \"This May Be the Most Important Medical Story of the Decade,\" New York Times, April 9, 2026","meta_description":"Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between the DNA where i…","key_points":[],"chapters":[],"topics":[],"duration_seconds":4791,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522/episodes/357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/sean-carroll-s-mindscape-science-society-philosophy-culture-arts-and-ideas-444522/357-jeff-coller-on-mrna-vaccines-and-bespoke-therapeutics.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}