{"podcast":{"title":"Race Against Mind: An Alzheimer's Prevention Investigation","slug":"race-against-mind-an-alzheimer-s-prevention-investigation-7840812","podcast_index_feed_id":7840812,"rss_url":"https://api.riverside.com/hosting/YblAo3PX.rss","website_url":"https://riverside.com","image_url":"https://hosting-media.riverside.com/media/podcasts/3c9d79af-54bc-4991-8978-301f76782263/logos/b2fa29e6-7d40-435e-b603-323696adc3d2.png","author":"Sarah Kuhn","episode_count":6,"summary":"Race Against Mind is an Alzheimer's prevention investigation hosted by Sarah Kuhn, a double APOE4 carrier with a family history of early-onset Alzheimer's disease. Instead of waiting, Sarah started asking a different question: what does the research actually say, and what happens when you take it seriously? Each episode goes deep on one piece of the prevention puzzle: exercise, sleep, metabolic health, alcohol, hormones. Sarah breaks down the science, examines how strong it really is, and shares what she did with that information in her own life. What worked, what didn't, and what she changed her mind about along the way. If you carry APOE4, have a family history of Alzheimer's, or simply refuse to leave your brain health to chance, this show is for you.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/race-against-mind-an-alzheimer-s-prevention-investigation-7840812"},"episode":{"title":"Ep. 5 Why Keto Backfired: MCT Oil, APOE4, and the Cholesterol I Couldn't Fix With Diet","slug":"ep-5-why-keto-backfired-mct-oil-apoe4-and-the-cholesterol-i-couldn-t-fix-with-diet","published_at":"2026-05-15T12:30:00+00:00","page_url":"https://stenobird.com/podcast/race-against-mind-an-alzheimer-s-prevention-investigation-7840812/ep-5-why-keto-backfired-mct-oil-apoe4-and-the-cholesterol-i-couldn-t-fix-with-diet","show_page_url":"https://stenobird.com/podcast/race-against-mind-an-alzheimer-s-prevention-investigation-7840812","url":"https://api.riverside.com/hosting-analytics/media/d35289fa0e3ac97990896ee00b9a1aba678b83b38d2edb0b9da9e73e78404702/eyJlcGlzb2RlSWQiOiJkMWMwOWQwMi1lNDA3LTQ2MGEtODMwMy1iNTdjMzM0MTgzYzUiLCJwb2RjYXN0SWQiOiIzYzlkNzlhZi01NGJjLTQ5OTEtODk3OC0zMDFmNzY3ODIyNjMiLCJhY2NvdW50SWQiOiI2OWNlYzc2YmQ2N2JlODBlMzA1OTE5MjAiLCJwYXRoIjoibWVkaWEvY2xpcHMvNmEwNjNjYmQ3YzcyYmQwMTdhYTM1ZjkyL3NhcmFoLWt1aG5zLXN0dWRpby1Hd0NRMC1jb21wb3Nlci0yMDI2LTUtMTRfXzIzLTIxLTEubXAzIn0=.mp3","audio_url":"https://api.riverside.com/hosting-analytics/media/d35289fa0e3ac97990896ee00b9a1aba678b83b38d2edb0b9da9e73e78404702/eyJlcGlzb2RlSWQiOiJkMWMwOWQwMi1lNDA3LTQ2MGEtODMwMy1iNTdjMzM0MTgzYzUiLCJwb2RjYXN0SWQiOiIzYzlkNzlhZi01NGJjLTQ5OTEtODk3OC0zMDFmNzY3ODIyNjMiLCJhY2NvdW50SWQiOiI2OWNlYzc2YmQ2N2JlODBlMzA1OTE5MjAiLCJwYXRoIjoibWVkaWEvY2xpcHMvNmEwNjNjYmQ3YzcyYmQwMTdhYTM1ZjkyL3NhcmFoLWt1aG5zLXN0dWRpby1Hd0NRMC1jb21wb3Nlci0yMDI2LTUtMTRfXzIzLTIxLTEubXAzIn0=.mp3","summary":"I've had high cholesterol since I was nine years old. I know, because my mom took away my chicken nuggets and put me on a diet. Three months later it came back to normal. Problem solved — or so I thought. It took until I was twenty-seven, two years into being vegetarian, to see a normal reading again. Total cholesterol of 139. I remember thinking: I finally figured it out. That one number became my proof of concept for the next 15 years. In this episode, I walk through five years of serious dietary intervention after getting my APOE4 result and a baseline LDL of 220. High Fiber Keto. Bulletproof coffee with MCT oil. KetoFlex 12/3. Extended fasting. Paleo. Plant-based. Supplements. And as of August 2025 — after all of it — my LDL was 149. Still high. Still not where it needs to be for someone with my risk profile. So I started a statin. This episode is about what that journey revealed — about the APOE4-specific reasons keto and MCT oil backfired, about why plant-based eating barely moved my numbers, and about what it looks like when the pillar you believed in most turns out not to be the lever you thought it was. I also get into why someone who's been eating well for twenty years shouldn't expect the same results from dietary intervention as someone who hasn't — and why that distinction matters more than most nutrition advice acknowledges. Note: this is the first of three nutrition episodes. Episode 6 covers the cholesterol mechanism and why APOE4 carriers have a fundamentally different lipid problem than most people. Episode 7 covers the broader nutrition and Alzheimer's prevention research — blueberries, the Mediterranean diet, omega-3s, and what the science actually says. Show Notes","meta_description":"I've had high cholesterol since I was nine years old. I know, because my mom took away my chicken nuggets and put me on a diet. Three months later it came…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1573,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/race-against-mind-an-alzheimer-s-prevention-investigation-7840812/episodes/ep-5-why-keto-backfired-mct-oil-apoe4-and-the-cholesterol-i-couldn-t-fix-with-diet/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/race-against-mind-an-alzheimer-s-prevention-investigation-7840812/ep-5-why-keto-backfired-mct-oil-apoe4-and-the-cholesterol-i-couldn-t-fix-with-diet.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}