{"podcast":{"title":"Paincast","slug":"paincast-6663821","podcast_index_feed_id":6663821,"rss_url":"https://feed.podbean.com/paincastpsd/feed.xml","website_url":"https://paincastpsd.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/16012985/Paincast_1400_x_1400_px__72bun5.png","author":"Canadian Physiotherapy Association Pain Science Division","episode_count":49,"summary":"Paincast is an effort of the Pain Science Division at the Canadian Physiotherapy Association. Paincast brings together researchers, clinicians, and students to facilitate knowledge translation, discussion, and critical thinking on topics related to pain and physiotherapy. The views expressed in each episode are of individual guests, do not constitute medical advice, and do not represent the views of the Pain Science Division or the Canadian Physiotherapy Association. Follow us on Instagram @paincast.psd. While there is an effort to incorporate research evidence in the episodes, and the topic is researched by the host, we recognize there is room for improvement and there is expertise in the community. As such, we invite constructive critique and that you inform us of any inadvertent errors, so that we may correct them. You may submit feedback through this form: https://forms.gle/BQ4KymfsCuTSFGaX7. You may contact Tiffany Tiu at paincast.psd@gmail.com if you have any other inquiries.","last_synced_at":"2026-06-19T12:19:09.199341+00:00","page_url":"https://stenobird.com/podcast/paincast-6663821"},"episode":{"title":"Ep42: Pain is More Than What the Knee Looks Like: Osteoarthritis Pain Mechanisms and Phenotypes with Dr. Lisa Carlesso","slug":"ep42-pain-is-more-than-what-the-knee-looks-like-osteoarthritis-pain-mechanisms-and-phenotypes-with-dr-lisa-carlesso","published_at":"2025-08-30T05:31:28+00:00","page_url":"https://stenobird.com/podcast/paincast-6663821/ep42-pain-is-more-than-what-the-knee-looks-like-osteoarthritis-pain-mechanisms-and-phenotypes-with-dr-lisa-carlesso","show_page_url":"https://stenobird.com/podcast/paincast-6663821","url":"https://paincastpsd.podbean.com/e/ep42-pain-is-more-than-what-the-knee-looks-like-osteoarthritis-pain-mechanisms-and-phenotypes-with-dr-lisa-carlesso/","audio_url":"https://mcdn.podbean.com/mf/web/wbfbe9e5zaa7u933/Ep42_LisaCarlesso.mp3","summary":"In this episode, we talked about The relationship between knee osteoarthritis (OA) pain and the stages of knee OA The different experiences of knee OA pain Pain phenotyping using Quantitative Sensory Testing and self-reported measures Dr. Lisa Carlesso is a an associate professor in the School of Rehabilitation Science at McMaster University in Canada with training as a clinical epidemiologist and a physical therapist. Her research program is broadly focussed on understanding the mechanisms and consequences of musculoskeletal pain with a particular focus on OA joint pain. Her research strives to optimize outcomes for people with chronic musculoskeletal disorders by 1. Understanding the complex mechanisms of acute and persistent pain through pain phenotyping to improve prognosis and treatment, 2. Using the understanding of endogenous modulation of pain to enhance conservative treatment options and 3. Improving the clinical measurement of pain. Resources Aoyagi, K., et al. (2022). Does weight-bearing versus non-weight-bearing pain reflect different pain mechanisms in knee osteoarthritis?: the Multicenter Osteoarthritis Study (MOST). Osteoarthritis and cartilage, 30(4), 545-550. Rankin, J., et al. (2022). Quantitative sensory testing protocols to evaluate central and peripheral sensitization in knee OA: a scoping review. Pain Medicine, 23(3), 526-557. Carlesso, L. C., et al. (2022). Association of pain sensitization and conditioned pain modulation to pain patterns in knee osteoarthritis. Arthritis care &amp; research, 74(1), 107-112. Carlesso, L. C. (2023). The impact of altered neural processing of nociceptive signals on physical function in people with knee OA—we know little and have much to learn. Osteoarthritis and Cartilage, 31(7), 844-846. Neelapala, Y. R., et al. 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