{"podcast":{"title":"Oxford Sparks Big Questions","slug":"oxford-sparks-big-questions-420721","podcast_index_feed_id":420721,"rss_url":"https://oxfordsparks.libsyn.com/rss","website_url":"https://www.oxfordsparks.ox.ac.uk/","image_url":"https://static.libsyn.com/p/assets/2/2/c/f/22cf91023fb4a322/Big_Questions_Podcast_pink_HIGH_RES.jpg","author":"Fiona Jones","episode_count":100,"summary":"'Will my bacon sandwich kill me?', 'Is vaping better than smoking?', 'How do you become an astronaut?' - just some of the Big Questions we ask some of the brightest minds behind Oxford science. Join us in each podcast as we explore a different area of science.","last_synced_at":"2026-06-18T00:18:10.275517+00:00","page_url":"https://stenobird.com/podcast/oxford-sparks-big-questions-420721"},"episode":{"title":"How can we use AI to make drugs?","slug":"how-can-we-use-ai-to-make-drugs","published_at":"2026-06-17T11:30:00+00:00","page_url":"https://stenobird.com/podcast/oxford-sparks-big-questions-420721/how-can-we-use-ai-to-make-drugs","show_page_url":"https://stenobird.com/podcast/oxford-sparks-big-questions-420721","url":"https://oxfordsparks.libsyn.com/how-can-we-use-ai-to-make-drugs","audio_url":"https://traffic.libsyn.com/secure/oxfordsparks/Ox-AI_drugs-v1.mp3?dest-id=790107","summary":"Put simply, most drugs work by binding to a protein and altering how they function. But how can we model how well a particular molecule will bind to a particular protein, and use that knowledge to help discover new treatments? In this episode, we talk to Prof Fergus Imrie from Oxford's Department of Statistics, who is one of the lead researchers on the OpenBind consortium. This project aims to create the world's largest open-access dataset of protein-ligand interactions, providing invaluable quantities of data for AI-driven drug discovery","meta_description":"Put simply, most drugs work by binding to a protein and altering how they function. But how can we model how well a particular molecule will bind to a par…","key_points":[],"chapters":[],"topics":[],"duration_seconds":728,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/oxford-sparks-big-questions-420721/episodes/how-can-we-use-ai-to-make-drugs/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/oxford-sparks-big-questions-420721/how-can-we-use-ai-to-make-drugs.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}