{"podcast":{"title":"Mikkipedia","slug":"mikkipedia-1319728","podcast_index_feed_id":1319728,"rss_url":"https://feeds.transistor.fm/mikkipedia","website_url":"https://www.mikkiwilliden.com","image_url":"https://img.transistorcdn.com/Rex5xizm5s75WEApb0hW2pnxZ3-n21cWTFT6Emw0820/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8wNjI2/NTEwMjAyMWQ2M2Iy/ZjliYjA4ZGFhMTBh/N2E2Ni5qcGc.jpg","author":"Mikki Williden","episode_count":485,"summary":"Mikkipedia is an exploration in all things health, well being, fitness, food and nutrition. I sit down with scientists, doctors, professors, practitioners and people who have a wealth of experience and have a conversation that takes a deep dive into their area of expertise. I love translating science into a language that people understand, so while some of the conversations will be pretty in-depth, you will come away with some practical tips that can be instigated into your everyday life. I hope you enjoy the show!","last_synced_at":"2026-07-15T06:20:29.552212+00:00","page_url":"https://stenobird.com/podcast/mikkipedia-1319728"},"episode":{"title":"Mini Mikkipedia - Weight Loss Injections: Science, Expectations, Side Effects","slug":"mini-mikkipedia-weight-loss-injections-science-expectations-side-effects","published_at":"2026-03-15T16:00:00+00:00","page_url":"https://stenobird.com/podcast/mikkipedia-1319728/mini-mikkipedia-weight-loss-injections-science-expectations-side-effects","show_page_url":"https://stenobird.com/podcast/mikkipedia-1319728","url":"https://share.transistor.fm/s/47f04866","audio_url":"https://media.transistor.fm/47f04866/3040403e.mp3","summary":"In this Mini Mikkipedia episode, Mikki breaks down the rapidly growing world of obesity pharmacotherapy, focusing on GLP-1 receptor agonists like semaglutide and the newer dual GLP-1/GIP drugs such as tirzepatide. With more people beginning these medications, understanding how they work—and how to use them effectively—has never been more important. Mikki explains the biology behind appetite regulation, the clinical trial data showing significant weight loss, and why these drugs are best viewed as long-term treatments rather than short courses. The episode also dives into the practical realities many people face once they start therapy: managing common gastrointestinal side effects, protecting muscle and bone during weight loss, and setting realistic expectations about outcomes. Whether you’re considering these medications yourself or supporting someone who is, this episode provides a clear, science-based guide to navigating the experience. Highlights: How GLP-1 and GLP-1/GIP medications regulate appetite and metabolism Clinical trial results: expected weight loss with semaglutide vs tirzepatide Why weight regain often occurs after stopping the drugs Practical strategies to manage nausea, constipation, and other GI side effects Protecting muscle and bone with protein intake and resistance training Contact Mikki: https://mikkiwilliden.com/ https://www.facebook.com/mikkiwillidennutrition https://www.instagram.com/mikkiwilliden/ https://linktr.ee/mikkiwilliden NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz Save 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz , www.nuzest.com.au or www.nuzest.com Curranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order","meta_description":"In this Mini Mikkipedia episode, Mikki breaks down the rapidly growing world of obesity pharmacotherapy, focusing on GLP-1 receptor agonists like semaglut…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1172,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/mikkipedia-1319728/episodes/mini-mikkipedia-weight-loss-injections-science-expectations-side-effects/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/mikkipedia-1319728/mini-mikkipedia-weight-loss-injections-science-expectations-side-effects.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}