{"podcast":{"title":"Mikkipedia","slug":"mikkipedia-1319728","podcast_index_feed_id":1319728,"rss_url":"https://feeds.transistor.fm/mikkipedia","website_url":"https://www.mikkiwilliden.com","image_url":"https://img.transistorcdn.com/Rex5xizm5s75WEApb0hW2pnxZ3-n21cWTFT6Emw0820/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8wNjI2/NTEwMjAyMWQ2M2Iy/ZjliYjA4ZGFhMTBh/N2E2Ni5qcGc.jpg","author":"Mikki Williden","episode_count":485,"summary":"Mikkipedia is an exploration in all things health, well being, fitness, food and nutrition. I sit down with scientists, doctors, professors, practitioners and people who have a wealth of experience and have a conversation that takes a deep dive into their area of expertise. I love translating science into a language that people understand, so while some of the conversations will be pretty in-depth, you will come away with some practical tips that can be instigated into your everyday life. I hope you enjoy the show!","last_synced_at":"2026-07-15T06:20:29.552212+00:00","page_url":"https://stenobird.com/podcast/mikkipedia-1319728"},"episode":{"title":"Mini Mikkipedia - Can Multivitamins Slow Brain Ageing?","slug":"mini-mikkipedia-can-multivitamins-slow-brain-ageing","published_at":"2026-05-24T17:00:00+00:00","page_url":"https://stenobird.com/podcast/mikkipedia-1319728/mini-mikkipedia-can-multivitamins-slow-brain-ageing","show_page_url":"https://stenobird.com/podcast/mikkipedia-1319728","url":"https://share.transistor.fm/s/d3c849ab","audio_url":"https://media.transistor.fm/d3c849ab/29bd32d6.mp3","summary":"This week’s Mini Mikkipedia takes a closer look at multivitamins, nutrient status, and whether a daily broad-spectrum supplement may support cognitive ageing. Mikki discusses the COSMOS trial, a large randomised, double-blind, placebo-controlled study that examined multivitamin use in older adults, with a particular focus on the cognitive findings from its ancillary studies. While the parent trial did not show significant benefits for cancer or cardiovascular disease, the cognitive studies found consistent benefits for episodic memory, with effects estimated to be equivalent to slowing cognitive ageing by around two to three years. Mikki also unpacks the limitations, including modest effect sizes, population generalisability, supplement formulation, and why supplements should support, not replace, the fundamentals of nutrition, exercise and sleep. Highlights: Why calorie deficits can increase the risk of micronutrient insufficiency What the COSMOS trial tells us about multivitamins and brain ageing The difference between observational research and randomised controlled trials Why episodic memory may be particularly responsive to nutrient status Why supplement quality, nutrient forms, and baseline deficiency risk matter Contact Mikki: https://mikkiwilliden.com/ https://www.facebook.com/mikkiwillidennutrition https://www.instagram.com/mikkiwilliden/ https://linktr.ee/mikkiwilliden NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz Save 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz , www.nuzest.com.au or www.nuzest.com Curranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order","meta_description":"This week’s Mini Mikkipedia takes a closer look at multivitamins, nutrient status, and whether a daily broad-spectrum supplement may support cognitive age…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1756,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/mikkipedia-1319728/episodes/mini-mikkipedia-can-multivitamins-slow-brain-ageing/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/mikkipedia-1319728/mini-mikkipedia-can-multivitamins-slow-brain-ageing.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}