{"podcast":{"title":"Metabolic Mind","slug":"metabolic-mind-6253550","podcast_index_feed_id":6253550,"rss_url":"https://feeds.captivate.fm/metabolic-mind/","website_url":"https://metabolicmind.org/","image_url":"https://artwork.captivate.fm/d5c870fb-4d35-464f-8bde-33ce9e2b58c4/MM-Podcast-cover-final.png","author":"Bret Scher","episode_count":224,"summary":"Metabolic Mind is working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. Metabolic interventions like ketogenic therapy are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. We explore topics that can help you understand how Metabolic Psychiatry might help you or a loved one treat mental disorders Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.","last_synced_at":"2026-07-24T00:18:08.497488+00:00","page_url":"https://stenobird.com/podcast/metabolic-mind-6253550"},"episode":{"title":"Rethinking Cholesterol Risk: What Lean Mass Hyper-Responders Reveal","slug":"rethinking-cholesterol-risk-what-lean-mass-hyper-responders-reveal","published_at":"2026-04-01T16:10:00+00:00","page_url":"https://stenobird.com/podcast/metabolic-mind-6253550/rethinking-cholesterol-risk-what-lean-mass-hyper-responders-reveal","show_page_url":"https://stenobird.com/podcast/metabolic-mind-6253550","url":"https://metabolicmind.org/","audio_url":"https://episodes.captivate.fm/episode/199ad695-32c0-42d2-be7c-b380d0272858.mp3","summary":"Is high LDL cholesterol always a red flag? For a growing group of people known as Lean Mass Hyper-Responders (LMHRs), the answer might not be so black and white. In this video, Dr. Bret Scher unpacks the science and questions behind LMHRs—metabolically healthy, lean individuals who see a dramatic rise in LDL cholesterol after starting a ketogenic diet. Unlike people with familial hypercholesterolemia (FH), their elevated LDL occurs in a unique metabolic context: low insulin, high HDL, low triglycerides, excellent metabolic health, and comes on only after adopting a ketogenic diet. 🔍 In this video, you'll learn: • What defines a Lean Mass Hyper-Responder • Why conventional cholesterol risk frameworks may not apply to LMHRs • The key differences between LMHRs and those with familial hypercholesterolemia • Why context, like insulin sensitivity and metabolic health, might matter • Why this phenomenon deserves thoughtful study, not assumptions This growing curiosity around LMHRs is the focus of a powerful new documentary: The Cholesterol Code . Featuring researchers, clinicians, and individuals living with this phenotype, the film challenges long-held beliefs about cholesterol, risk, and metabolic health, and opens the door to a more nuanced conversation 🎬 Real change starts with real conversations. Join us in sharing The Cholesterol Code, a powerful film that challenges outdated thinking about cholesterol and heart health. Sign up to host a screening or find one near you at 🔗 https://cholesterolcodemovie.com/host-a-screening/ . Together, we can reach the people who need this most. 🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode. #MetabolicMind #KetogenicTher…","meta_description":"Is high LDL cholesterol always a red flag? For a growing group of people known as Lean Mass Hyper-Responders (LMHRs), the answer might not be so black and…","key_points":[],"chapters":[],"topics":[],"duration_seconds":347,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/metabolic-mind-6253550/episodes/rethinking-cholesterol-risk-what-lean-mass-hyper-responders-reveal/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/metabolic-mind-6253550/rethinking-cholesterol-risk-what-lean-mass-hyper-responders-reveal.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}